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Review
. 2021 Jan 8;49(D1):D10-D17.
doi: 10.1093/nar/gkaa892.

Database resources of the National Center for Biotechnology Information

Eric W Sayers  1 , Jeffrey Beck  1 , Evan E Bolton  1 , Devon Bourexis  1 , James R Brister  1 , Kathi Canese  1 , Donald C Comeau  1 , Kathryn Funk  1 , Sunghwan Kim  1 , William Klimke  1 , Aron Marchler-Bauer  1 , Melissa Landrum  1 , Stacy Lathrop  1 , Zhiyong Lu  1 , Thomas L Madden  1 , Nuala O'Leary  1 , Lon Phan  1 , Sanjida H Rangwala  1 , Valerie A Schneider  1 , Yuri Skripchenko  1 , Jiyao Wang  1 , Jian Ye  1 , Barton W Trawick  1 , Kim D Pruitt  1 , Stephen T Sherry  1
Affiliations
Review

Database resources of the National Center for Biotechnology Information

Eric W Sayers et al. Nucleic Acids Res. .

Abstract

The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed® database of citations and abstracts published in life science journals. The Entrez system provides search and retrieval operations for most of these data from 34 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Custom implementations of the BLAST program provide sequence-based searching of many specialized datasets. New resources released in the past year include a new PubMed interface and NCBI datasets. Additional resources that were updated in the past year include PMC, Bookshelf, Genome Data Viewer, SRA, ClinVar, dbSNP, dbVar, Pathogen Detection, BLAST, Primer-BLAST, IgBLAST, iCn3D and PubChem. All of these resources can be accessed through the NCBI home page at https://www.ncbi.nlm.nih.gov.

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Figures

Figure 1.
Figure 1.
Annual growth rates of the number of records in each Entrez database as of 9 September 2020.
Figure 2.
Figure 2.
Landing page for the new NCBI Datasets product (https://www.ncbi.nlm.nih.gov/datasets/) that provides packaged downloads of genomic datasets using either a web interface, an API, or a UNIX/LINUX command-line tool.
See this image and copyright information in PMC

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