Post-Transplant Pregnancy and Contraception
- PMID: 33731339
- PMCID: PMC8763163
- DOI: 10.2215/CJN.14100820
Post-Transplant Pregnancy and Contraception
Abstract
Placed in a historical context, this overview focuses on post-transpant pregnancy, fatherhood, and contraception in women and men. The critical importance of early reproductive counseling because of improved sexual function and the early return of ovulation and menses post-transplant is emphasized. We explain the decision making regarding contraception choices. The available data on the safety of immunosuppressive drugs in pregnancy, and for men desiring fatherhood, are detailed. The risk of maternal ingestion of mycophenolate products on the in utero fetus is considered and contrasted with the lack of concern for their use by men fathering children. Pregnancy risks to the allograft, baby, and mother are discussed. An infant's exposure to specific immunosuppressant medications through breastfeeding is reviewed. The ethics and realities of post-transplant parenthood are explored.
Keywords: Kidney Transplantation Series; contraception; post-transplant; pregnancy.
Copyright © 2022 by the American Society of Nephrology.
Comment in
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Thinking Outside the Box: Novel Kidney Protective Strategies in Kidney Transplantation.Clin J Am Soc Nephrol. 2021 Dec;16(12):1890-1897. doi: 10.2215/CJN.15070920. Epub 2021 Mar 23. Clin J Am Soc Nephrol. 2021. PMID: 33757985 Free PMC article.
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