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Randomized Controlled Trial
. 2021 Jun 21;16(1):178.
doi: 10.1186/s13019-021-01525-8.

Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction

Xiaojiao Hao  1 , Damin Huang  1 , Zhaoxia Wang  1 , Jinchun Zhang  1 , Hongqiang Liu  1 , Yingmin Lu  2
Affiliations
Randomized Controlled Trial

Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction

Xiaojiao Hao et al. J Cardiothorac Surg. .

Erratum in

Abstract

Background: Drug-coated balloon (DCB) is a new technology that has emerged in recent years and has been proven to be effective and safe in the treatment of in-stent restenosis. The purpose of this article is to observe the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction.

Method: We selected 80 patients admitted to the hospital for STEMI from January 2018 to December 2019. The subjects were randomly divided into a Yinyi (Liaoning) Biotech Bingo Drug Coated Balloon treatment group (balloon group, n = 38) and a drug-eluting stent (DES) treatment group (stent group, n = 42). Patients were followed up to understand the incidence of major adverse cardiovascular events (MACE) at 1 month, 6 months and 1 year after surgery. Coronary angiography was rechecked 1 year after surgery to understand the late lumen loss (LLL) in the two groups.

Result: During the one-year follow-up, the LLL of the target lesion in the balloon group was -0.12±0.46 mm, while the target lesion in the stent group was 0.14±0.37 mm ( P <0.05). Within 1 year, the incidence of MACE in the balloon group was 11%, while the incidence of MACE in the stent group was 12%. There was no significant difference between the two groups.

In conclusion: When PCI is used for STEMI, only DCB therapy is safe and effective, and has shown good clinical effects during a one-year follow-up period.

Keywords: Acute ST-segment elevation myocardial infarction; Drug-coated balloon; Late lumen loss.

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Conflict of interest statement

The authors declare that they have no competing interests.

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