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. 2021 Oct:84:102415.
doi: 10.1016/j.parint.2021.102415. Epub 2021 Jul 1.

The Pan African Vivax and Ovale Network (PAVON): Refocusing on Plasmodium vivax, ovale and asymptomatic malaria in sub-Saharan Africa

Isaac K Quaye  1 , Larysa Aleksenko  2 , Claude Oeuvray  3 , Delenasaw Yewhalaw  4 , Nancy Duah  5 , Ben Gyan  5 , Daniel H Haiyambo  6 , Ghyslaine Bruna Djeunang Dongho  7 , Ruth-Ayanful Torgby  8 , Linda Amoah  5 , Mahdi Abdel Hamid  9 , Solomon Worku  10 , Assefa Ashenafi Bahiti  11 , Harriet Akello Pasquale  12 , Mimie Bitshi  13 , Isidore Troare  14 , Amidou Diarra  15 , Eric Njunju  16 , Mamoudou Cisse  14 , Issiaka Soulama  15 , Ragnessi Justin Savadogo  17 , Saadou Issifou  18 , Amadou Niangaly  19 , Laurent Dembele  19 , Beatrice Greco  3
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Free article

The Pan African Vivax and Ovale Network (PAVON): Refocusing on Plasmodium vivax, ovale and asymptomatic malaria in sub-Saharan Africa

Isaac K Quaye et al. Parasitol Int. 2021 Oct.
Free article

Abstract

The recent World Malaria report shows that progress in malaria elimination has stalled. Current data acquisition by NMCPs depend on passive case detection and clinical reports focused mainly on Plasmodium falciparum (Pf). In recent times, several countries in sub-Saharan Africa have reported cases of Plasmodium vivax (Pv) with a considerable number being Duffy negative. The burden of Pv and Plasmodium ovale (Po) appear to be more than acknowledged. Similarly, the contribution of asymptomatic malaria in transmission is hardly considered by NMCPs in Africa. Inclusion of these as targets in malaria elimination agenda is necessary to achieve elimination goal, as these harbor hypnozoites. The Pan African Vivax and Ovale Network (PAVON) is a new consortium of African Scientists working in Africa on the transmission profile of Pv and Po. The group collaborates with African NMCPs to train in Plasmodium molecular diagnostics, microscopy, and interpretation of molecular data from active surveys to translate into policy. Details of the mission, rational and modus operandi of the group are outlined.

Keywords: Asymptomatic transmission; PAVON; Plasmodium ovale; Plasmodium vivax transmission; Sub-Saharan Africa.

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