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Review
. 2021 Jul 16;10(14):3154.
doi: 10.3390/jcm10143154.

Preeclampsia and Cardiovascular Risk for Offspring

Wiktor Wojczakowski  1 , Żaneta Kimber-Trojnar  1 , Filip Dziwisz  2 , Magdalena Słodzińska  1 , Hubert Słodziński  3 , Bożena Leszczyńska-Gorzelak  1
Affiliations
Review

Preeclampsia and Cardiovascular Risk for Offspring

Wiktor Wojczakowski et al. J Clin Med. .

Abstract

There is growing evidence of long-term cardiovascular sequelae in children after in utero exposure to preeclampsia. Maternal hypertension and/or placental ischaemia during pregnancy increase the risk of hypertension, stroke, diabetes, and cardiovascular disease (CVD) in the offspring later in life. The mechanisms associated with CVD seem to be a combination of genetic, molecular, and environmental factors which can be defined as fetal and postnatal programming. The aim of this paper is to discuss the relationship between pregnancy complicated by preeclampsia and possibility of CVD in the offspring. Unfortunately, due to its multifactorial nature, a clear dependency mechanism between preeclampsia and CVD is difficult to establish.

Keywords: cardiovascular risk; fetal programming; gestational hypertension; offspring; preeclampsia.

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Conflict of interest statement

The authors declare no conflict of interest.

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