Exercise capacity impairment after COVID-19 pneumonia is mainly caused by deconditioning

doi:10.1183/13993003.01136-2021

Comment

. 2021 Dec 31;59(1):2101136.

doi: 10.1183/13993003.01136-2021. Print 2022 Jan.

Exercise capacity impairment after COVID-19 pneumonia is mainly caused by deconditioning

Affiliations

¹ Clinics of Respiratory Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
² Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel and University of Basel, Basel, Switzerland.
³ Dept of Radiology, University Hospital Basel and University of Basel, Basel, Switzerland.
⁴ Division of Internal Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
⁵ Dept of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.
⁶ Dept of Intensive Care Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
⁷ Clinics of Respiratory Medicine, University Hospital Basel and University of Basel, Basel, Switzerland katrin.hostettler@usb.ch.

PMID: 34737222
PMCID: PMC8573604
DOI: 10.1183/13993003.01136-2021

Comment

Exercise capacity impairment after COVID-19 pneumonia is mainly caused by deconditioning

Kathleen Jahn et al. Eur Respir J. 2021.

. 2021 Dec 31;59(1):2101136.

doi: 10.1183/13993003.01136-2021. Print 2022 Jan.

Authors

Affiliations

¹ Clinics of Respiratory Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
² Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel and University of Basel, Basel, Switzerland.
³ Dept of Radiology, University Hospital Basel and University of Basel, Basel, Switzerland.
⁴ Division of Internal Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
⁵ Dept of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.
⁶ Dept of Intensive Care Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
⁷ Clinics of Respiratory Medicine, University Hospital Basel and University of Basel, Basel, Switzerland katrin.hostettler@usb.ch.

PMID: 34737222
PMCID: PMC8573604
DOI: 10.1183/13993003.01136-2021

Abstract

Not pulmonary factors, but physical deconditioning is the main limiting factor of exercise capacity in patients after severe COVID-19 pneumonitis. This underscores the importance of an early rehabilitative intervention in these patients. https://bit.ly/2XVvr6C

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Conflict of interest statement

Conflict of interest: S. Bassetti participated on an advisory board for Pharming Technologies BV, outside the submitted work. All other authors have nothing to disclose.

Comment on

Cardiopulmonary exercise capacity and limitations 3 months after COVID-19 hospitalisation.
Skjørten I, Ankerstjerne OAW, Trebinjac D, Brønstad E, Rasch-Halvorsen Ø, Einvik G, Lerum TV, Stavem K, Edvardsen A, Ingul CB. Skjørten I, et al. Eur Respir J. 2021 Aug 26;58(2):2100996. doi: 10.1183/13993003.00996-2021. Print 2021 Aug. Eur Respir J. 2021. PMID: 34210791 Free PMC article.

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References

1. Li X, Zeng W, Li X, et al. . CT imaging changes of coronavirus disease 2019 (COVID-19): a multi-center study in Southwest China. J Transl Med 2020; 18: 154. doi:10.1186/s12967-020-02324-w - DOI - PMC - PubMed
1. Huang Y, Tan C, Wu J, et al. . Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase. Respir Res 2020; 21: 163. doi:10.1186/s12931-020-01429-6 - DOI - PMC - PubMed
1. Guler SA, Ebner L, Beigelman C, et al. . Pulmonary function and radiological features 4 months after COVID-19: first results from the national prospective observational Swiss COVID-19 lung study. Eur Respir J 2021; 57: 2003690. doi:10.1183/13993003.03690-2020 - DOI - PMC - PubMed
1. Sava M, Sommer G, Daikeler T, et al. . Ninety-day outcome of patients with severe COVID-19 treated with tocilizumab - a single centre cohort study. Swiss Med Wkly 2021; 151: w20550. doi:10.4414/smw.2021.20550 - DOI - PubMed
1. Palange P, Ward SA, Carlsen KH, et al. . Recommendations on the use of exercise testing in clinical practice. Eur Respir J 2007; 29: 185–209. doi:10.1183/09031936.00046906 - DOI - PubMed

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[1] Li X, Zeng W, Li X, et al. . CT imaging changes of coronavirus disease 2019 (COVID-19): a multi-center study in Southwest China. J Transl Med 2020; 18: 154. doi:10.1186/s12967-020-02324-w - DOI - PMC - PubMed

[2] Li X, Zeng W, Li X, et al. . CT imaging changes of coronavirus disease 2019 (COVID-19): a multi-center study in Southwest China. J Transl Med 2020; 18: 154. doi:10.1186/s12967-020-02324-w - DOI - PMC - PubMed

[3] Huang Y, Tan C, Wu J, et al. . Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase. Respir Res 2020; 21: 163. doi:10.1186/s12931-020-01429-6 - DOI - PMC - PubMed

[4] Huang Y, Tan C, Wu J, et al. . Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase. Respir Res 2020; 21: 163. doi:10.1186/s12931-020-01429-6 - DOI - PMC - PubMed

[5] Guler SA, Ebner L, Beigelman C, et al. . Pulmonary function and radiological features 4 months after COVID-19: first results from the national prospective observational Swiss COVID-19 lung study. Eur Respir J 2021; 57: 2003690. doi:10.1183/13993003.03690-2020 - DOI - PMC - PubMed

[6] Guler SA, Ebner L, Beigelman C, et al. . Pulmonary function and radiological features 4 months after COVID-19: first results from the national prospective observational Swiss COVID-19 lung study. Eur Respir J 2021; 57: 2003690. doi:10.1183/13993003.03690-2020 - DOI - PMC - PubMed

[7] Sava M, Sommer G, Daikeler T, et al. . Ninety-day outcome of patients with severe COVID-19 treated with tocilizumab - a single centre cohort study. Swiss Med Wkly 2021; 151: w20550. doi:10.4414/smw.2021.20550 - DOI - PubMed

[8] Sava M, Sommer G, Daikeler T, et al. . Ninety-day outcome of patients with severe COVID-19 treated with tocilizumab - a single centre cohort study. Swiss Med Wkly 2021; 151: w20550. doi:10.4414/smw.2021.20550 - DOI - PubMed

[9] Palange P, Ward SA, Carlsen KH, et al. . Recommendations on the use of exercise testing in clinical practice. Eur Respir J 2007; 29: 185–209. doi:10.1183/09031936.00046906 - DOI - PubMed

[10] Palange P, Ward SA, Carlsen KH, et al. . Recommendations on the use of exercise testing in clinical practice. Eur Respir J 2007; 29: 185–209. doi:10.1183/09031936.00046906 - DOI - PubMed

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Exercise capacity impairment after COVID-19 pneumonia is mainly caused by deconditioning

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Exercise capacity impairment after COVID-19 pneumonia is mainly caused by deconditioning

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