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. 2022 Mar;13(3):429-431.
doi: 10.1111/jdi.13730. Epub 2021 Dec 15.

Unmet needs in current clinical practice for insulinoma: Lessons from nationwide studies in Japan

Takaaki Murakami  1 , Daisuke Yabe  2 , Nobuya Inagaki  1
Affiliations

Unmet needs in current clinical practice for insulinoma: Lessons from nationwide studies in Japan

Takaaki Murakami et al. J Diabetes Investig. 2022 Mar.

Abstract

Unmet clinical needs for the management of insulinoma include a low proportion of patients having surgical treatment, postoperative diabetes mellitus, and residual hypoglycemia. Glucagon-like peptide-1 (GLP-1) receptor-targeted imaging such as that using [18 F]FB(ePEG12)12-exendin-4 positron emission tomography (PET) is promising and may fill unmet clinical needs.

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Figure 1
Figure 1
Unmet clinical needs for the management of insulinoma. Glucagon‐like peptide‐1 (GLP‐1) receptor‐targeted imaging such as that using [18F]FB(ePEG12)12‐exendin‐4 positron emission tomography (PET) are promising and may fill unmet clinical needs. Structure of [18F]FB(ePEG12)12‐exendin‐4 and a [18F]FB(ePEG12)12‐exendin‐4 PET/computed tomography (CT) abdominal image of a healthy subject are shown.
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