Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments
- PMID: 35107261
- PMCID: PMC8851693
- DOI: 10.1021/acs.est.1c04780
Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments
Erratum in
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Correction to Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments.Environ Sci Technol. 2022 May 17;56(10):6790. doi: 10.1021/acs.est.2c01379. Epub 2022 Apr 25. Environ Sci Technol. 2022. PMID: 35467352 Free PMC article. No abstract available.
Abstract
We measured the concentrations of 837 hydroxylated polychlorinated biphenyls (OH-PCBs, in 275 chromatographic peaks) and 209 polychlorinated biphenyls (PCBs, in 174 chromatographic peaks) in sediments from New Bedford Harbor in Massachusetts, Altavista wastewater lagoon in Virginia, and the Indiana Harbor and Ship Canal in Indiana, USA and in the original commercial PCB mixtures Aroclors 1016, 1242, 1248, and 1254. We used the correlation between homologues and the peak responses to quantify the full suite of OH-PCBs including those without authentic standards available. We found that OH-PCB levels are approximately 0.4% of the PCB levels in sediments and less than 0.0025% in Aroclors. The OH-PCB congener distributions of sediments are different from those of Aroclors and are different according to sites. We also identified a previously unknown compound, 4-OH-PCB52, which together with 4'-OH-PCB18 made up almost 30% of the OH-PCBs in New Bedford Harbor sediments but less than 1.2% in the Aroclors and 3.3% in any other sediments. This indicates site-specific environmental transformations of PCBs to OH-PCBs. We conclude that the majority of OH-PCBs in these sediments are generated in the environment. Our findings suggest that these toxic breakdown products of PCBs are prevalent in PCB-contaminated sediments and present an emerging concern for humans and ecosystems.
Keywords: Altavista; Aroclors; Indiana Harbor and Ship Canal; New Bedford Harbor; OH-PCBs; sediment.
Conflict of interest statement
The authors declare no competing financial interest.
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References
-
- Letcher R. J.; Klasson-Wehler E.; Bergman A.. Methyl Sulfone and Hydroxylated Metabolites of Polychlorinated Biphenyls. In Volume 3 Anthropogenic Compounds Part K; Hutzinger O., Paasivirta J., Eds.; Springer Berlin Heidelberg: Berlin, Heidelberg, 2000; pp 315–359.
-
- Agency for Toxic Substances and Disease Registry (ATSDR) . Toxicological Profile for Polychlorinated Biphenyls (PCBs); U.S. Department of Health & Human Services: Atlanta, GA, USA, 2000. URL: https://www.atsdr.cdc.gov/toxprofiles/tp17.pdf. - PubMed
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