Malaria diagnostic methods with the elimination goal in view
- PMID: 35460369
- PMCID: PMC9033523
- DOI: 10.1007/s00436-022-07512-9
Malaria diagnostic methods with the elimination goal in view
Abstract
Malaria control measures have been in use for years but have not completely curbed the spread of infection. Ultimately, global elimination is the goal. A major playmaker in the various approaches to reaching the goal is the issue of proper diagnosis. Various diagnostic techniques were adopted in different regions and geographical locations over the decades, and these have invariably produced diverse outcomes. In this review, we looked at the various approaches used in malaria diagnostics with a focus on methods favorably used during pre-elimination and elimination phases as well as in endemic regions. Microscopy, rapid diagnostic testing (RDT), loop-mediated isothermal amplification (LAMP), and polymerase chain reaction (PCR) are common methods applied depending on prevailing factors, each with its strengths and limitations. As the drive toward the elimination goal intensifies, the search for ideal, simple, fast, and reliable point-of-care diagnostic tools is needed more than ever before to be used in conjunction with a functional surveillance system supported by the ideal vaccine.
Keywords: Diagnostics; Elimination; Malaria; Microscopy; RDT; Surveillance; Vaccine.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Conflict of interest statement
The authors declare no competing interests.
Similar articles
-
Evaluation of the colorimetric malachite green loop-mediated isothermal amplification (MG-LAMP) assay for the detection of malaria species at two different health facilities in a malaria endemic area of western Kenya.Malar J. 2020 Sep 9;19(1):329. doi: 10.1186/s12936-020-03397-0. Malar J. 2020. PMID: 32907582 Free PMC article.
-
Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for screening malaria in peripheral and placental blood samples from pregnant women in Colombia.Malar J. 2018 Jul 13;17(1):262. doi: 10.1186/s12936-018-2403-5. Malar J. 2018. PMID: 30005616 Free PMC article.
-
Diagnostic performance of the loop-mediated isothermal amplification (LAMP) based illumigene® malaria assay in a non-endemic region.Malar J. 2017 Oct 17;16(1):418. doi: 10.1186/s12936-017-2065-8. Malar J. 2017. PMID: 29041927 Free PMC article.
-
Diagnostic tools in childhood malaria.Parasit Vectors. 2018 Jan 23;11(1):53. doi: 10.1186/s13071-018-2617-y. Parasit Vectors. 2018. PMID: 29361963 Free PMC article. Review.
-
Malaria diagnostic update: From conventional to advanced method.J Clin Lab Anal. 2022 Apr;36(4):e24314. doi: 10.1002/jcla.24314. Epub 2022 Mar 4. J Clin Lab Anal. 2022. PMID: 35247002 Free PMC article. Review.
Cited by
-
Molecular Research on Plasmodium Infection and Immunity.Int J Mol Sci. 2024 Apr 8;25(7):4133. doi: 10.3390/ijms25074133. Int J Mol Sci. 2024. PMID: 38612941 Free PMC article.
-
The Malaria Burden: A South African Perspective.J Trop Med. 2024 Feb 23;2024:6619010. doi: 10.1155/2024/6619010. eCollection 2024. J Trop Med. 2024. PMID: 38434493 Free PMC article. Review.
-
Evaluation of the malaria elimination programme in Muara Enim Regency: a qualitative study from Indonesia.Malar J. 2024 Feb 12;23(1):43. doi: 10.1186/s12936-024-04857-7. Malar J. 2024. PMID: 38347633 Free PMC article.
-
Head-to-head comparison of two loop-mediated isothermal amplification (LAMP) kits for diagnosis of malaria in a non-endemic setting.Malar J. 2023 Dec 13;22(1):377. doi: 10.1186/s12936-023-04809-7. Malar J. 2023. PMID: 38093251 Free PMC article.
-
A novel duplex qualitative real-time PCR assay for the detection and differentiation of Plasmodium ovale curtisi and Plasmodium ovale wallikeri malaria.medRxiv [Preprint]. 2023 Oct 31:2023.10.31.23297819. doi: 10.1101/2023.10.31.23297819. medRxiv. 2023. PMID: 37961397 Free PMC article. Preprint.
References
-
- Abdul-Ghani R (2015) Malaria research priorities in Yemen: paving the way for malaria elimination. Yemeni J Med Sci 9(1). 10.20428/yjms.9.1.e
-
- Aborode A, Anifowoshe O, Ifeoluwapo Ayodele T, Rebecca Iretiayo A, Oluwafemi David O (2020) Impact of COVID- 19 on education in Sub-Saharan Africa. Preprints, 2020070027. 1–26. 10.20944/preprints202007.0027.v1. online from https://www.preprints.org/manuscript/202007.0027/v1. Accessed 29 Mar 2002
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
Research Materials