Personalized Nutrition in the Management of Female Infertility: New Insights on Chronic Low-Grade Inflammation
- PMID: 35565885
- PMCID: PMC9105997
- DOI: 10.3390/nu14091918
Personalized Nutrition in the Management of Female Infertility: New Insights on Chronic Low-Grade Inflammation
Abstract
Increasing evidence on the significance of nutrition in reproduction is emerging from both animal and human studies, suggesting a mutual association between nutrition and female fertility. Different "fertile" dietary patterns have been studied; however, in humans, conflicting results or weak correlations are often reported, probably because of the individual variations in genome, proteome, metabolome, and microbiome and the extent of exposure to different environmental conditions. In this scenario, "precision nutrition", namely personalized dietary patterns based on deep phenotyping and on metabolomics, microbiome, and nutrigenetics of each case, might be more efficient for infertile patients than applying a generic nutritional approach. In this review, we report on new insights into the nutritional management of infertile patients, discussing the main nutrigenetic, nutrigenomic, and microbiomic aspects that should be investigated to achieve effective personalized nutritional interventions. Specifically, we will focus on the management of low-grade chronic inflammation, which is associated with several infertility-related diseases.
Keywords: chronic low-grade inflammation; epigenetics; infertility; microbiota; nutrigenetic; nutrigenomics; precision nutrition.
Conflict of interest statement
The authors declare no conflict of interest.
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References
-
- Ferraretti A., Nygren K., Andersen A.N., De Mouzon J., Kupka M., Calhaz-Jorge C., Wyns C., Gianaroli L., Goossens V., European IVF-Monitoring Consortium (EIM), European Society of Human Reproduction and Embryology (ESHRE) et al. Trends over 15 years in ART in Europe: An analysis of 6 million cycles†. Hum. Reprod. Open. 2017;2017:hox012. doi: 10.1093/hropen/hox012. - DOI - PMC - PubMed
-
- De Geyter C., Calhaz-Jorge C., Kupka M.S., Wyns C., Mocanu E., Motrenko T., Scaravelli G., Smeenk J., Vidakovic S., Goossens V., et al. ART in Europe, 2014: Results generated from European registries by ESHRE: The European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE) Hum. Reprod. 2018;33:1586–1601. doi: 10.1093/humrep/dey242. - DOI - PubMed
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