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. 2022 Aug 29:14:936027.
doi: 10.3389/fnagi.2022.936027. eCollection 2022.

The effects of different types of Tai Chi exercises on motor function in patients with Parkinson's disease: A network meta-analysis

Honghui Lei  1 , Zhen Ma  1 , Kexin Tian  1 , Ke Liu  1 , Jiaying Wang  1 , Xiangyu Zhu  1 , Baohong Mi  1 , Ying Chen  2 , Qihao Yang  3 , Huili Jiang  1
Affiliations

The effects of different types of Tai Chi exercises on motor function in patients with Parkinson's disease: A network meta-analysis

Honghui Lei et al. Front Aging Neurosci. .

Abstract

Background: Tai Chi can show improvement in balance and motor ability of elderly patients with PD. However, there were few reports on differences in outcomes associated with different types of Tai Chi on improving exercise capacity in elderly patients with PD. We compared the improvement of motor function in Parkinson's patients with different types of Tai Chi, for finding an optimal intervention.

Methods: The following databases were searched from the beginning of the establishment of each database to 10 January 2022: PubMed, EMBASE, The Cochrane Library, CNKI, Wanfang Database, and VIP Database. Randomized controlled trials incorporating different types of Tai Chi for PD were included. The outcome measures were UPDRSIII and BBS. NMA was conducted using Stata 15.0 based on a frequentist framework.

Results: A total of twenty trials were eligible, including 996 participants. In conventional meta-analysis, as for the UPDRSIII scale, 24-form simplified Tai Chi (SMD = -1.272, 95% CI [-2.036, -0.508], P < 0.05, I2 > 50%), Tai Chi exercise program (SMD = -0.839, 95% CI [-1.828, 0.151], P > 0.05, I2 > 50%), 8-form simplified Yang style Tai Chi (SMD = -0.325, 95% CI [-1.362, 0.713], P > 0.05, I2 > 50%), and 8-form simplified Chen style Tai Chi (SMD = -0.28, 95% CI [-0.97, 0.42], P > 0.05, I2 > 50%) were statistically more efficient than the control group. For BBS outcome, 24-form simplified Tai Chi (MD = 3.979, 95% CI [3.364, 4.595], P < 0.05, I2 <50%), Tai Chi exercise program (MD = 5.00, 95% CI [2.07, 7.93], P > 0.05, I2 > 50%), and 8-form simplified Chen style Tai Chi (MD = 1.25, 95% CI [0.52, 1.98], P < 0.05, I2 > 50%) were better than the control group. In the network meta-analysis, the results of UPDRSIII were as follows: 24-form > TCEP > 8-form YS > 8-form CS > control. The ranking probability of BBS was as follows: TCEP > 24-form > 8-form CS > control.

Conclusion: Among the four treatments studied, 24-form Tai Chi and Tai Chi exercise programs have shown better efficacy than other types. Our study provides new insights into exercise therapy for PD and may contribute to the formulation of a clinical exercise prescription.

Systematic review registration: Identifier: CRD42021285005.

Keywords: Parkinson's disease; Tai Chi; exercise therapy; movement disorders; network meta-analysis.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Schematic illustration of the literature search and study selection criteria.
Figure 2
Figure 2
Quality assessment of included studies.
Figure 3
Figure 3
The network structure of the analyzed treatment comparisons for the outcome of UPDRSIII.
Figure 4
Figure 4
UPDRSIII: Interval plot comparing the effectiveness of the four treatments. 24-form: 24-form simplified Tai Chi; TCEP: Tai Chi exercise program; 8-form YS: 8-form simplified Yang style Tai Chi; 8-form CS: 8-form simplified Chen style Tai Chi.
Figure 5
Figure 5
UPDRSIII rank probability.
Figure 6
Figure 6
UPDRSIII: Funnel plot showing the publication bias of the included randomized controlled trials. (A) control group; (B) 24-form simplified Tai Chi; (C) Tai Chi exercise program; (D) 8-form simplified Yang style Tai Chi; (E) 8-form simplified Chen style Tai Chi.
Figure 7
Figure 7
The network structure of the analyzed treatment comparisons for the outcome of BBS.
Figure 8
Figure 8
BBS: Interval plot comparing the effectiveness of the four treatments. 24-form: 24-form simplified Tai Chi; TCEP: Tai Chi exercise program; 8-form CS: 8-form simplified Chen style Tai Chi.
Figure 9
Figure 9
BBS rank probability.
Figure 10
Figure 10
BBS: Funnel plot showing the publication bias of the included randomized controlled trials. (A) control group; (B) 24-form simplified Tai Chi; (C) Tai Chi exercise program; (D) 8-form simplified Chen style Tai Chi.
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References

    1. Alonso-Frech F., Sanahuja J. J., Rodriguez A. M. (2011). Exercise and physical therapy in early management of Parkinson disease. Neurologist 17, 47–53. 10.1097/NRL.0b013e31823968ec - DOI - PubMed
    1. Amano S., Nocera J. R., Vallabhajosula S., Juncos J. L., Gregor R. J., Waddell D. E., et al. . (2013). The effect of Tai Chi exercise on gait initiation and gait performance in persons with Parkinson's disease. Parkinsonism Relat. Disord. 19, 955–960. 10.1016/j.parkreldis.2013.06.007 - DOI - PMC - PubMed
    1. Ascherio A., Schwarzschild M. A. (2016). The epidemiology of Parkinson's disease: risk factors and prevention. Lancet Neurol. 15, 1257–1272. 10.1016/S1474-4422(16)30230-7 - DOI - PubMed
    1. Balestrino R., Schapira A. H. V. (2020). Parkinson disease. Eur. J. Neurol. 27, 27–42. 10.1111/ene.14108 - DOI - PubMed
    1. Berg K. O., Wood-Dauphinee S. L., Williams J. I., Maki B. (1992). Measuring Balance in the Elderly: Validation of an Instrument. Montreal: McGill University. - PubMed

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