doi: 10.7164/antibiotics.39.502.
A novel macrolide antibiotic, notonesomycin A
- PMID: 3710911
- DOI: 10.7164/antibiotics.39.502
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A novel macrolide antibiotic, notonesomycin A
J Antibiot (Tokyo).
1986 Apr.
Free article
Abstract
Fermentation of Streptomyces aminophilus subsp. notonesogenes 647-AV1 produced a mixture of antifungal antibiotics. Notonesomycin A, the main component has been characterized as a new macrolide antibiotic containing a sulfate group, a malonate moiety, two deoxysugars and a 1,3,4-trisubstituted benzene system in the molecule. It was active against some fungi and Gram-positive bacteria in vitro and effective against the sheath blight disease of rice plant in a green house test.
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