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Randomized Controlled Trial
. 2023 Mar;23(1):584-591.
doi: 10.4314/ahs.v23i1.61.

The effect of short-term vitamin D on the antioxidant capacity following exhaustive aerobic exercise

Vahid Parvizi Mastali  1 , Rastegar Hoseini  1 , Mohammad Azizi  1
Affiliations
Randomized Controlled Trial

The effect of short-term vitamin D on the antioxidant capacity following exhaustive aerobic exercise

Vahid Parvizi Mastali et al. Afr Health Sci. 2023 Mar.

Abstract

Background: Exhaustive Aerobic Exercise (EAE) increases the production of free radicals and oxidative stress in the body. One of the most effective approaches to reduce EAE-induced oxidative stress is antioxidant supplementation.

Objectives: Therefore, the present study investigated the effect of short-term Vitamin D (Vit D) supplementation on antioxidant capacity in inactive men following an EAE session.

Methods: In this clinical trial, 24 non-athlete men were randomly divided into Experimental (Exp; n = 12) and Control (C; n = 12) groups. Exp received 2,000 IU of Vit D daily for six weeks (42 days), while C received a lactose placebo daily with the same color, shape, and warmth percentage. EAE sessions were performed on a treadmill before and after six weeks of supplementation.

Results: The results showed that EAE increased antioxidant capacity and Vit D (P<0.05). Compared with C, six weeks of Vit D supplementation significantly increased superoxide dismutase (P=0.001), glutathione peroxidase (P=0.011), catalase (P=0.018), peroxidase (P=0.001), and Vit D (P=0.001), in the Exp at the Post 2 stage.

Conclusion: Finally, short-term Vit D supplementation could be recommended to non-athlete men deciding to participate in EAE to prevent oxidative damage.

Keywords: Antioxidant Capacity; Exhaustive Aerobic Exercise; Overweight; Vitamin D.

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Conflict of interest statement

The authors declare no competing financial interests.

Figures

Figure 1
Figure 1
Consort flow diagram for the study
Figure 2
Figure 2
Overview of the study design
Figure 3
Figure 3
Antioxidant capacity levels at different time points in Exp and C BW: Bodyweight; BMI: Body Mass Index; PFB: Percent Body Fat; WHR: Waist-Hip Ratio P values superscript with “a” is calculated using an independent t-test for comparing Δ between groups. P values superscript with “b” is calculated using dependent t-test for comparing pre-test and post-test within groups
Figure 4
Figure 4
Vit D levels at different time points in Exp and C α: Significantly different compared with Post 1. £: Significantly different compared with Pre 2. €: Significantly different compared with Post 2. ¥: Significantly different comparing Exp and C.
See this image and copyright information in PMC

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