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Review
. 2023 Nov;89(5):387-391.
doi: 10.1111/cod.14396. Epub 2023 Aug 13.

Contact dermatitis associated with an anti-haemorrhoidal ointment containing ephedrine and benzocaine: Case report and literature review

Luis Feito-Sancho  1 , Dulce M Arranz-Sánchez  1 , Gema Vázquez-Contreras  1 , Abraham Santa-Cruz Martín  1 , Tatiana Sanz-Sánchez  1
Affiliations
Review

Contact dermatitis associated with an anti-haemorrhoidal ointment containing ephedrine and benzocaine: Case report and literature review

Luis Feito-Sancho et al. Contact Dermatitis. 2023 Nov.
No abstract available

Keywords: adverse drug reaction; allergic contact dermatitis; case report; irritant contact dermatitis; patch test.

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References

REFERENCES

    1. Marín-Piñero D, Iglesias-Sancho M, Company-Quiroga J, et al. Multiple perianal ulcers related to use of a hemorrhoidal ointment with the active ingredients triamcinolone acetonide, lidocaine, and pentosan polysulfate sodium: a series of 11 Spanish patients. Actas Dermosifiliogr. 2021;112:654-660.
    1. Aksoy B. Ulceration of breast's skin due to topical corticosteroid abuse. J Dermatol Res Ther. 2017;1:36-39.
    1. Gimeno-Castillo J, Parrón AM, de la Torre RME, Etxebarria AB, Río IG. Perianal ulcers and erosions after using an anti-hemorrhoid ointment. Med Clin. 2023;160:282.
    1. Carmona-Pérez MV, Lanz CAG, Rodriguez PG, González-Cuevas JF. Large perianal defect due to treatment with antihemorrhoidal ointment in an immunosuppressed patient. Aten Primaria. 2023;55:102502.
    1. Robson KJ, Maughan JA, Purcell SD, Petersen MJ, Haefner HK, Lowe L. Erosive papulonodular dermatosis associated with topical benzocaine: a report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet's erosive dermatitis are a disease spectrum. J Am Acad Dermatol. 2006;55:74-80.

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