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Case Reports
. 2023 Aug 14;109(3):608-610.
doi: 10.4269/ajtmh.23-0180. Print 2023 Sep 6.

Case Report: Hemophagocytic Lymphohistiocytosis Secondary to Plasmodium ovale wallikeri Infection

María Novella-Mena  1 , Purificación Cantudo-Muñoz  2 , José David Tallón-Pérez  3 , María Del Mar Gómez-Rodríguez  4 , Gerardo Rojo-Marcos  1   5
Affiliations
Case Reports

Case Report: Hemophagocytic Lymphohistiocytosis Secondary to Plasmodium ovale wallikeri Infection

María Novella-Mena et al. Am J Trop Med Hyg. .

Abstract

We report the first known case of hemophagocytic lymphohistiocytosis (HLH) secondary to imported Plasmodium ovale wallikeri infection in a 58-year-old white woman. A delayed diagnosis of malaria and HLH was made after protracted fever and pancytopenia failed to respond adequately to antimalarial treatment, which required intravenous methylprednisolone and gamma-globulin therapy to resolve.

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