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. 2023 Dec 20;22(1):72.
doi: 10.1186/s12937-023-00903-3.

Comparison of energy expenditure measurements by a new basic respiratory room vs. classical ventilated hood

Timia Van Soom  1 , Wiebren Tjalma  2   3   4 , Ulrike Van Daele  1   5 , Nick Gebruers #  6   7 , Eric van Breda #  8
Affiliations

Comparison of energy expenditure measurements by a new basic respiratory room vs. classical ventilated hood

Timia Van Soom et al. Nutr J. .

Abstract

Background: Nutritional support is often based on predicted resting energy expenditure (REE). In patients, predictions seem invalid. Indirect calorimetry is the gold standard for measuring EE. For assessments over longer periods (up to days), room calorimeters are used. Their design makes their use cumbersome, and warrants improvements to increase utility. Current study aims to compare data on momentary EE, obtained by a basic respiration room vs. classical ventilated hood. The objective is to compare results of the basic room and to determine its 1)reliability for measuring EE and 2)sensitivity for minute changes in activity.

Methods: Two protocols (P1; P2)(n = 62; 25 men/37 women) were applied. When measured by hood, participants in both protocols were in complete rest (supine position). When assessed by room, participants in P1 were instructed to stay half-seated while performing light desk work; in P2 participants were in complete rest mimicking hood conditions. The Omnical calorimeter operated both modalities. Following data were collected/calculated: Oxygen uptake ([Formula: see text] O2(ml/min)), carbon dioxide production ([Formula: see text] CO2ml/min), 24h_EE (kcal/min), and respiratory exchange ratio (RER). Statistical analyses were done between modalities and between protocols. The agreement between 24h_EE, [Formula: see text] O2 and [Formula: see text] CO2 obtained by both modalities was investigated by linear regression. Reliability analysis on 24h_EE determined ICC.

Results: No significant differences were found for 24h_EE and [Formula: see text] O2. [Formula: see text] CO2 significantly differed in P1 + P2, and P2 (hood > room). RER was significantly different (hood > room) for P1 + P2 and both protocols individually. Reliability of 24h_EE between modalities was high. Modality-specific results were not different between protocols.

Discussion/conclusion: The room is valid for assessing momentary EE. Minute changes in activity lead to a non-significant increase in EE and significant increase in RER. The significant difference in [Formula: see text] CO2 for hood might be related to perceived comfort. More research is necessary on determinants of RER, type (intensity) of activity, and restlessness. The design of the room facilitates metabolic measurements in research, with promising results for future clinical use.

Keywords: Energy expenditure; Indirect calorimetry; Nutritional assessment; Respiratory room; Ventilated hood.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Modalities used for measuring energy expenditure. Left: Ventilated hood; Right: Basic respiratory room
Fig. 2
Fig. 2
Bland–Altman plot of the agreement between modalities. Upper: Bland–Altman plot for 24h_EE measured by room and hood; Middle: Bland–Altman plot for VO2 measured by room and hood; Lower: Bland–Altman plot for VCO2 measured by room and hood; DELTA24h_EE: Difference between 24h_EE measured by hood and room for subjects of P1 + P2; MEAN24h_EE: Mean of 24h_EE measured by hood and room for subjects of P1 + P2; DELTA_ VO2: Difference between VO2 measured by hood and room for subjects of P1 + P2; MEAN_ VO2: Mean of VO2 measured by hood and room for subjects of P1 + P2; DELTA_ VCO2: Difference between VCO2 measured by hood and room for subjects of P1 + P2; MEAN_ VCO2: Mean of VCO2 measured by hood and room for subjects of P1 + P2; UB: Upper boundary; LB: Lower boundary
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