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Review
. 2024 Jan 16;5(1):50-60.
doi: 10.14744/hf.2022.2022.0052. eCollection 2024.

Evidence-based herbal treatments in liver diseases

Methiye Mancak  1 , Dudu Altintas  2 , Yasemin Balaban  3 , Ufuk Koca Caliskan  1
Affiliations
Review

Evidence-based herbal treatments in liver diseases

Methiye Mancak et al. Hepatol Forum. .

Abstract

The liver is the main organ for metabolic and detoxification reactions in the body. Therefore, its diseases can be associated with both metabolic disorders, such as insulin resistance, obesity, diabetes, or dyslipidemia, and exogenous insults such as drugs, xenobiotics, or alcohol. Indeed, lifestyle changes are the primary approaches for the prevention and treatment of liver diseases. Since ancient times, herbals have also been used for preventive and therapeutic purposes, because of their anti-apoptotic, anti-inflammatory, and antioxidant effects. Here, the literature was reviewed for potential therapeutic effects of plants and their compounds by including in vitro and in vivo studies, as well as clinical trials. Although the available data imply some beneficial roles of herbals on the liver, the indications and posology of specific plants need to be clarified through multicenter, randomized clinical trials.

Keywords: Alcoholic liver disease; fibrosis; herbal; liver disease; nonalcoholic liver disease; plant; silymarin.

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
Herbal component for liver diseases.
Figure 2
Figure 2
Herbal drug for liver diseases.
See this image and copyright information in PMC

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