Measuring pulsatile cortical blood flow and volume during carotid endarterectomy
- PMID: 38495722
- PMCID: PMC10942688
- DOI: 10.1364/BOE.507730
Measuring pulsatile cortical blood flow and volume during carotid endarterectomy
Abstract
Carotid endarterectomy (CEA) involves removal of plaque in the carotid artery to reduce the risk of stroke and improve cerebral perfusion. This study aimed to investigate the utility of assessing pulsatile blood volume and flow during CEA. Using a combined near-infrared spectroscopy/diffuse correlation spectroscopy instrument, pulsatile hemodynamics were assessed in 12 patients undergoing CEA. Alterations to pulsatile amplitude, pulse transit time, and beat morphology were observed in measurements ipsilateral to the surgical side. The additional information provided through analysis of pulsatile hemodynamic signals has the potential to enable the discovery of non-invasive biomarkers related to cortical perfusion.
© 2024 Optica Publishing Group.
Conflict of interest statement
At the time of the study, MAF had a financial interest in 149 Medical, Inc., a company developing DCS technology for assessing and monitoring CBF in newborn infants, which is now dissolved. MAF’s interests were reviewed and managed by Massachusetts General Hospital and Mass General Brigham in accordance with their conflict-of-interest policies. A.I.Z., K.K., K.C.W., E.T.P., and M.B.R. have nothing to report.
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