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. 2024 Jun 12;29(12):2804.
doi: 10.3390/molecules29122804.

Nanoliposomal Encapsulation of Capparis spinosa Extract and Its Application in Jelly Formulation

Younes Zahedi  1 , Rezvan Shaddel  1 , Masoumeh Salamatian  1 , Antoni Szumny  2
Affiliations
Free PMC article

Nanoliposomal Encapsulation of Capparis spinosa Extract and Its Application in Jelly Formulation

Younes Zahedi et al. Molecules. .
Free PMC article

Abstract

This research aimed to encapsulate the Capparis spinosa fruit extract to increase its stability for incorporation into food products such as jelly or jelly powder. After extraction, the nanoliposomes containing the extract were prepared in ratios of 60-0, 50-10, 40-20, and 30-30 lecithin-to-cholesterol. The effects of lecithin-to-cholesterol concentrations on the related parameters were then evaluated. The results showed that the average particle size was in the range of 95.05 to 164.25 nm, and with an increasing cholesterol concentration, the particle size of the nanoliposomes increased. The addition of cholesterol increased the zeta potential from -60.40 to -68.55 millivolt. Furthermore, cholesterol led to an increase in encapsulation efficiency, and even improved the stability of phenolic compounds loaded in nanoliposomes during storage time. Fourier transform infrared (FTIR) spectroscopy confirmed the successful loading of the extract. Field emission scanning electron microscopy (FE-SEM) analysis revealed nano-sized spherical and almost-elliptical liposomes. For jelly powders, the water solubility index ranged from 39.5 to 43.7% (p > 0.05), and the hygroscopicity values ranged between 1.22 and 9.36 g/100 g (p < 0.05). In conclusion, nanoencapsulated Capparis spinosa extract displayed improved stability and can be used in jelly preparation without any challenge or unfavorable perception.

Keywords: Capparis spinosa; jelly powder; nanoliposome; phenolic compounds.

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References

    1. Biotechnol Annu Rev. 2001;7:59-85 - PubMed
    1. J Agric Food Chem. 2011 Dec 28;59(24):13004-11 - PubMed
    1. Int J Pharm. 2001 May 21;219(1-2):61-72 - PubMed
    1. Adv Pharm Bull. 2014 Dec;4(Suppl 2):569-75 - PubMed
    1. J Control Release. 2008 Apr 21;127(2):97-109 - PubMed

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