Recognition of influenza A virus nucleoprotein by an H-2-restricted cytotoxic T-cell clone
- PMID: 6200990
- DOI: 10.1016/0042-6822(84)90413-6
Recognition of influenza A virus nucleoprotein by an H-2-restricted cytotoxic T-cell clone
Abstract
Cytotoxic T-cell clones raised against X-31 (H3N2) influenza virus in C57BL/6 mice can be directed against an influenza A virus subtype specific determinant (1). A representative T-cell clone (A3.1) has been used in combination with a set of genetically typed recombinant viruses, to show that the A/PR/8/34 nucleoprotein can be responsible for cytotoxic T-lymphocyte recognition of infected target cells.
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