doi: 10.1038/298391a0.
A bifunctional gene product involved in two phases of the yeast cell cycle
- PMID: 7045699
- DOI: 10.1038/298391a0
Item in Clipboard
A bifunctional gene product involved in two phases of the yeast cell cycle
Nature.
.
Abstract
The cell cycle in Saccharomyces cerevisiae is divided into two distinct phases. Unbudded, mononucleate cells in the G1 phase can react to relevant environmental changes by mating, sporulating, or by entering stationary phase. DNA synthesis and bud initiation occur almost simultaneously and mark 'commitment' to the completion of mitosis. Temperature-sensitive mutations at the cdc28 locus are known to cause arrest in the G1 phase of the cell cycle at the restrictive temperature. Here we show that the cdc28 gene product is also active in post-G1 cell cycle functions, and that a different property of the gene product may be required for each phase of the cycle in which it acts.
Similar articles
-
Cell cycle phase expansion in nitrogen-limited cultures of Saccharomyces cerevisiae.J Cell Biol. 1980 Apr;85(1):96-107. doi: 10.1083/jcb.85.1.96. J Cell Biol. 1980. PMID: 6988443 Free PMC article.
-
A temperature-sensitive N-glycosylation mutant of S. cerevisiae that behaves like a cell-cycle mutant.Exp Cell Res. 1984 Feb;150(2):309-13. doi: 10.1016/0014-4827(84)90573-1. Exp Cell Res. 1984. PMID: 6363106
-
The GTP-binding protein Rho1p is required for cell cycle progression and polarization of the yeast cell.J Cell Biol. 1999 Jul 26;146(2):373-87. doi: 10.1083/jcb.146.2.373. J Cell Biol. 1999. PMID: 10427091 Free PMC article.
-
Stationary phase in the yeast Saccharomyces cerevisiae.Microbiol Rev. 1993 Jun;57(2):383-401. doi: 10.1128/mr.57.2.383-401.1993. Microbiol Rev. 1993. PMID: 8393130 Free PMC article. Review.
-
The central dogma of cell biology.Cell Biol Int Rep. 1981 Jun;5(6):539-49. doi: 10.1016/s0309-1651(81)80002-1. Cell Biol Int Rep. 1981. PMID: 7018703 Review.
Cited by
-
Synchronization of Saccharomyces cerevisiae Cells for Analysis of Progression Through the Cell Cycle.Methods Mol Biol. 2022;2579:145-168. doi: 10.1007/978-1-0716-2736-5_12. Methods Mol Biol. 2022. PMID: 36045205
-
Connections between the cell cycle, cell adhesion and the cytoskeleton.Philos Trans R Soc Lond B Biol Sci. 2019 Aug 19;374(1779):20180227. doi: 10.1098/rstb.2018.0227. Epub 2019 Jul 1. Philos Trans R Soc Lond B Biol Sci. 2019. PMID: 31431178 Free PMC article. Review.
-
Phosphorus Deficiency Inhibits Cell Division But Not Growth in the Dinoflagellate Amphidinium carterae.Front Microbiol. 2016 Jun 1;7:826. doi: 10.3389/fmicb.2016.00826. eCollection 2016. Front Microbiol. 2016. PMID: 27313570 Free PMC article.
-
Genetic and physical interaction of Ssp1 CaMKK and Rad24 14-3-3 during low pH and osmotic stress in fission yeast.Open Biol. 2014 Jan 22;4(1):130127. doi: 10.1098/rsob.130127. Open Biol. 2014. PMID: 24451546 Free PMC article.
-
A quantitative model for cyclin-dependent kinase control of the cell cycle: revisited.Philos Trans R Soc Lond B Biol Sci. 2011 Dec 27;366(1584):3572-83. doi: 10.1098/rstb.2011.0082. Philos Trans R Soc Lond B Biol Sci. 2011. PMID: 22084384 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
