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. 1998 Feb 6;279(5352):876-8.
doi: 10.1126/science.279.5352.876.

Meiotic synapsis in the absence of recombination

K S McKim  1 , B L Green-Marroquin, J J Sekelsky, G Chin, C Steinberg, R Khodosh, R S Hawley
Affiliations

Meiotic synapsis in the absence of recombination

K S McKim et al. Science. .

Abstract

Although in Saccharomyces cerevisiae the initiation of meiotic recombination, as indicated by double-strand break formation, appears to be functionally linked to the initiation of synapsis, meiotic chromosome synapsis in Drosophila females occurs in the absence of meiotic exchange. Electron microscopy of oocytes from females homozygous for either of two meiotic mutants (mei-W68 and mei-P22), which eliminate both meiotic crossing over and gene conversion, revealed normal synaptonemal complex formation. Thus, synapsis in Drosophila is independent of meiotic recombination, consistent with a model in which synapsis is required for the initiation of meiotic recombination. Furthermore, the basic processes of early meiosis may have different functional or temporal relations, or both, in yeast and Drosophila.

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Comment in

  • Meiosis. Searching for a partner.
    Haber JE. Haber JE. Science. 1998 Feb 6;279(5352):823-4. doi: 10.1126/science.279.5352.823. Science. 1998. PMID: 9480551 No abstract available.

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