Non-invasive transcranial ultrasound stimulation for neuromodulation

G Darmani, TO Bergmann, KB Pauly, CF Caskey… - Clinical …, 2022 - Elsevier
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …

[HTML][HTML] Human Studies of Transcranial Ultrasound neuromodulation: A systematic review of effectiveness and safety

C Sarica, JF Nankoo, A Fomenko, TC Grippe… - Brain stimulation, 2022 - Elsevier
Background Transcranial ultrasound stimulation (TUS) is gaining traction as a safe and non-
invasive technique in human studies. There has been a rapid increase in TUS human …

Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans

W Legon, TF Sato, A Opitz, J Mueller, A Barbour… - Nature …, 2014 - nature.com
Improved methods of noninvasively modulating human brain function are needed. Here we
probed the influence of transcranial focused ultrasound (tFUS) targeted to the human …

Transcranial pulsed ultrasound stimulates intact brain circuits

Y Tufail, A Matyushov, N Baldwin, ML Tauchmann… - Neuron, 2010 - cell.com
Electromagnetic-based methods of stimulating brain activity require invasive procedures or
have other limitations. Deep-brain stimulation requires surgically implanted electrodes …

Transcranial focused ultrasound stimulation of human primary visual cortex

W Lee, HC Kim, Y Jung, YA Chung, IU Song, JH Lee… - Scientific reports, 2016 - nature.com
Transcranial focused ultrasound (FUS) is making progress as a new non-invasive mode of
regional brain stimulation. Current evidence of FUS-mediated neurostimulation for humans …

Neuromodulation with single‐element transcranial focused ultrasound in human thalamus

W Legon, L Ai, P Bansal, JK Mueller - Human brain mapping, 2018 - Wiley Online Library
Transcranial focused ultrasound (tFUS) has proven capable of stimulating cortical tissue in
humans. tFUS confers high spatial resolutions with deep focal lengths and as such, has the …

Remote excitation of neuronal circuits using low-intensity, low-frequency ultrasound

WJ Tyler, Y Tufail, M Finsterwald, ML Tauchmann… - PloS one, 2008 - journals.plos.org
Possessing the ability to noninvasively elicit brain circuit activity yields immense
experimental and therapeutic power. Most currently employed neurostimulation methods …

Focused ultrasound modulates region-specific brain activity

SS Yoo, A Bystritsky, JH Lee, Y Zhang, K Fischer… - Neuroimage, 2011 - Elsevier
We demonstrated the in vivo feasibility of using focused ultrasound (FUS) to transiently
modulate (through either stimulation or suppression) the function of regional brain tissue in …

Ultrasonic neuromodulation by brain stimulation with transcranial ultrasound

Y Tufail, A Yoshihiro, S Pati, MM Li, WJ Tyler - nature protocols, 2011 - nature.com
Brain stimulation methods are indispensable to the study of brain function. They have also
proven effective for treating some neurological disorders. Historically used for medical …

Noninvasive neuromodulation with ultrasound? A continuum mechanics hypothesis

WJ Tyler - The Neuroscientist, 2011 - journals.sagepub.com
Deep brain stimulation and vagal nerve stimulation are therapeutically effective in treating
some neurological diseases and psychiatric disorders. Optogenetic-based neurostimulation …