The alphaviruses: gene expression, replication, and evolution

JH Strauss, EG Strauss - Microbiological reviews, 1994 - Am Soc Microbiol
The alphaviruses are a genus of 26 enveloped viruses that cause disease in humans and
domestic animals. Mosquitoes or other hematophagous arthropods serve as vectors for …

A structural and functional perspective of alphavirus replication and assembly

J Jose, JE Snyder, RJ Kuhn - Future microbiology, 2009 - Taylor & Francis
Alphaviruses are small, spherical, enveloped, positive-sense ssRNA viruses responsible for
a considerable number of human and animal diseases. Alphavirus members include …

Recognition of transmembrane helices by the endoplasmic reticulum translocon

T Hessa, H Kim, K Bihlmaier, C Lundin, J Boekel… - Nature, 2005 - nature.com
Membrane proteins depend on complex translocation machineries for insertion into target
membranes. Although it has long been known that an abundance of nonpolar residues in …

A new generation of animal cell expression vectors based on the Semliki Forest virus replicon

P Liljeström, H Garoff - Bio/technology, 1991 - nature.com
We have developed a novel DNA expression system, based on the Semliki Forest virus
(SFV) replicon, which combines a wide choice of animal cell hosts, high efficiency and ease …

Nucleocapsid‐independent assembly of coronavirus‐like particles by co‐expression of viral envelope protein genes.

H Vennema, GJ Godeke, JW Rossen… - The EMBO …, 1996 - embopress.org
Budding of enveloped viruses has been shown to be driven by interactions between a
nucleocapsid and a proteolipid membrane. By contrast, we here describe the assembly of …

Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo

P Yin, BJ Davenport, JJ Wan, AS Kim… - Nature …, 2023 - nature.com
Chikungunya virus (CHIKV) has recently emerged to cause millions of human infections
worldwide. Infection can induce the formation of long intercellular extensions that project …

β-d-N4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome

N Urakova, V Kuznetsova, DK Crossman… - Journal of …, 2018 - Am Soc Microbiol
Venezuelan equine encephalitis virus (VEEV) is a representative member of the New World
alphaviruses. It is transmitted by mosquito vectors and causes highly debilitating disease in …

Adding the third dimension to virus life cycles: three-dimensional reconstruction of icosahedral viruses from cryo-electron micrographs

TS Baker, NH Olson, SD Fuller - Microbiology and Molecular …, 1999 - Am Soc Microbiol
Viruses are cellular parasites. The linkage between viral and host functions makes the study
of a viral life cycle an important key to cellular functions. A deeper understanding of many …

Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses

FS Varghese, P Kaukinen, S Gläsker, M Bespalov… - Antiviral research, 2016 - Elsevier
Chikungunya virus (CHIKV) is an arthritogenic arbovirus of the Alphavirus genus, which has
infected millions of people after its re-emergence in the last decade. In this study, a BHK cell …

Infectious transcripts and cDNA clones of RNA viruses.

JC Boyer, AL Haenni - 1994 - cabidigitallibrary.org
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