An introduction to high intensity focused ultrasound: systematic review on principles, devices, and clinical applications

Z Izadifar, Z Izadifar, D Chapman, P Babyn - Journal of clinical medicine, 2020 - mdpi.com
Ultrasound can penetrate deep into tissues and interact with human tissue via thermal and
mechanical mechanisms. The ability to focus an ultrasound beam and its energy onto …

Overview of therapeutic ultrasound applications and safety considerations

DL Miller, NB Smith, MR Bailey… - Journal of ultrasound …, 2012 - Wiley Online Library
Applications of ultrasound in medicine for therapeutic purposes have been accepted and
beneficial uses of ultrasonic biological effects for many years. Low‐power ultrasound of …

[HTML][HTML] A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer

G Dimcevski, S Kotopoulis, T Bjånes, D Hoem… - Journal of Controlled …, 2016 - Elsevier
Background The primary aim of our study was to evaluate the safety and potential toxicity of
gemcitabine combined with microbubbles under sonication in inoperable pancreatic cancer …

High intensity focused ultrasound: surgery of the future?

JE Kennedy, GR ter Haar… - The British journal of …, 2003 - academic.oup.com
For 50 years, high intensity focused ultrasound (HIFU) has been a subject of interest for
medical research. HIFU causes selective tissue necrosis in a very well defined volume, at a …

[HTML][HTML] Therapeutic applications of ultrasound

G Ter Haar - Progress in biophysics and molecular biology, 2007 - Elsevier
Therapeutic applications of ultrasound predate its use in imaging. A range of biological
effects can be induced by ultrasound, depending on the exposure levels used. At low levels …

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood–brain barrier disruption

M Kinoshita, N McDannold… - Proceedings of the …, 2006 - National Acad Sciences
Antibody-based anticancer agents are promising chemotherapeutic agents. Among these
agents, Herceptin (trastuzumab), a humanized anti-human epidermal growth factor receptor …

Experimental demonstration of noninvasive transskull adaptive focusing based on prior computed tomography scans

JF Aubry, M Tanter, M Pernot, JL Thomas… - The Journal of the …, 2003 - pubs.aip.org
Developing minimally invasive brain surgery by high-intensity focused ultrasound beams is
of great interest in cancer therapy. However, the skull induces strong aberrations both in …

MR imaging–guided focused ultrasound surgery of uterine leiomyomas: a feasibility study

CMC Tempany, EA Stewart, N McDannold, BJ Quade… - Radiology, 2003 - pubs.rsna.org
The feasibility and safety of magnetic resonance (MR) imaging–guided focused ultrasound
surgery for uterine leiomyomas is reported. Sequential sonications were delivered to nine …

Physical mechanisms of the therapeutic effect of ultrasound (a review)

MR Bailey, VA Khokhlova, OA Sapozhnikov, SG Kargl… - Acoustical …, 2003 - Springer
Therapeutic ultrasound is an emerging field with many medical applications. High intensity
focused ultrasound (HIFU) provides the ability to localize the deposition of acoustic energy …

[HTML][HTML] Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids

EA Stewart, J Rabinovici, CMC Tempany, Y Inbar… - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: To assess outcomes at 6 and 12 months after magnetic resonance–guided
focused ultrasound surgery (MRgFUS) for symptomatic uterine leiomyomas. DESIGN …