Mammalian stress granules and P bodies at a glance
Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-
based cellular compartments that assemble in response to stress. SGs and PBs form …
based cellular compartments that assemble in response to stress. SGs and PBs form …
Stress granules: the Tao of RNA triage
P Anderson, N Kedersha - Trends in biochemical sciences, 2008 - cell.com
Cytoplasmic RNA structures such as stress granules (SGs) and processing bodies (PBs) are
functional byproducts of mRNA metabolism, sharing substrate mRNA, dynamic properties …
functional byproducts of mRNA metabolism, sharing substrate mRNA, dynamic properties …
Mechanistic insights into mammalian stress granule dynamics
The accumulation of stalled translation preinitiation complexes (PICs) mediates the
condensation of stress granules (SGs). Interactions between prion-related domains and …
condensation of stress granules (SGs). Interactions between prion-related domains and …
Translation inhibition and stress granules in the antiviral immune response
C McCormick, DA Khaperskyy - Nature Reviews Immunology, 2017 - nature.com
Efficient viral gene expression is threatened by cellular stress response programmes that
rapidly reprioritize the translation machinery in response to varied environmental assaults …
rapidly reprioritize the translation machinery in response to varied environmental assaults …
Mammalian stress granules and processing bodies
N Kedersha, P Anderson - Methods in enzymology, 2007 - Elsevier
The packaging of cytoplasmic mRNA into discrete RNA granules regulates gene expression
by delaying the translation of specific transcripts. Specialized RNA granules found in germ …
by delaying the translation of specific transcripts. Specialized RNA granules found in germ …
Alphavirus RNA synthesis and non-structural protein functions
JC Rupp, KJ Sokoloski… - Journal of General …, 2015 - microbiologyresearch.org
The members of the genus Alphavirus are positive-sense RNA viruses, which are
predominantly transmitted to vertebrates by a mosquito vector. Alphavirus disease in …
predominantly transmitted to vertebrates by a mosquito vector. Alphavirus disease in …
(ADP-ribosyl) hydrolases: structure, function, and biology
ADP-ribosylation is an intricate and versatile posttranslational modification involved in the
regulation of a vast variety of cellular processes in all kingdoms of life. Its complexity derives …
regulation of a vast variety of cellular processes in all kingdoms of life. Its complexity derives …
Viral and cellular mRNA translation in coronavirus-infected cells
K Nakagawa, KG Lokugamage, S Makino - Advances in virus research, 2016 - Elsevier
Coronaviruses have large positive-strand RNA genomes that are 5′ capped and 3′
polyadenylated. The 5′-terminal two-thirds of the genome contain two open reading frames …
polyadenylated. The 5′-terminal two-thirds of the genome contain two open reading frames …
Tinkering with translation: protein synthesis in virus-infected cells
D Walsh, MB Mathews, I Mohr - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Viruses are obligate intracellular parasites, and their replication requires host cell functions.
Although the size, composition, complexity, and functions encoded by their genomes are …
Although the size, composition, complexity, and functions encoded by their genomes are …
The wisdom of crowds: regulating cell function through condensed states of living matter
S Alberti - Journal of cell science, 2017 - journals.biologists.com
Our understanding of cells has progressed rapidly in recent years, mainly because of
technological advances. Modern technology now allows us to observe molecular processes …
technological advances. Modern technology now allows us to observe molecular processes …