Ultrasound for the brain: a review of physical and engineering principles, and clinical applications

W Qiu, A Bouakaz, EE Konofagou… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
The emergence of new ultrasound technologies has improved our understanding of the
brain functions and offered new opportunities for the treatment of brain diseases. Ultrasound …

A review of low-intensity transcranial focused ultrasound for clinical applications

A Bystritsky, AS Korb - Current Behavioral Neuroscience Reports, 2015 - Springer
The field of therapeutic focused ultrasound neuromodulation has made great advances in
the last few years. While no clinical trials of focused ultrasound neuromodulation are yet …

Influence of the pressure field distribution in transcranial ultrasonic neurostimulation

Y Younan, T Deffieux, B Larrat, M Fink… - Medical …, 2013 - Wiley Online Library
Purpose: Low‐intensity focused ultrasound has been shown to stimulate the brain
noninvasively and without noticeable tissue damage. Such a noninvasive and localized …

The potential of transskull ultrasound therapy and surgery using the maximum available skull surface area

J Sun, K Hynynen - The Journal of the Acoustical Society of America, 1999 - pubs.aip.org
Based on previous studies, the transskull ultrasound field is re-examined by utilizing the
maximum available skull surface area. The source is assumed to be in direct contact with the …

A 200–1380-kHz Quadrifrequency Focused Ultrasound Transducer for Neurostimulation in Rodents and Primates: Transcranial In Vitro Calibration and Numerical …

C Constans, T Deffieux, P Pouget… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Low intensity transcranial focused ultrasound has been demonstrated to produce
neuromodulation in both animals and humans. Primarily for technical reasons, frequency is …

A review of low-intensity focused ultrasound for neuromodulation

H Baek, KJ Pahk, H Kim - Biomedical engineering letters, 2017 - Springer
Abstracts The ability of ultrasound to be focused into a small region of interest through the
intact skull within the brain has led researchers to investigate its potential therapeutic uses …

A review of low-intensity focused ultrasound pulsation

A Bystritsky, AS Korb, PK Douglas, MS Cohen… - Brain stimulation, 2011 - Elsevier
With the recent approval by the Food and Drug Administration (FDA) of Deep Brain
Stimulation (DBS) for Parkinson's Disease, dystonia and obsessive compulsive disorder …

Transcranial ultrasound focus reconstruction with phase and amplitude correction

J White, GT Clement, K Hynynen - ieee transactions on …, 2005 - ieeexplore.ieee.org
Therapeutic and diagnostic ultrasound procedures performed noninvasively through the
skull require a reliable method for maintaining acoustic focus integrity after transmission …

Focused ultrasound modifications of neural circuit activity in a mammalian brain

MR Bachtold, PC Rinaldi, JP Jones, F Reines… - Ultrasound in medicine …, 1998 - Elsevier
The application of focused, pulsed ultrasound was studied as a method of modifying the
activity of a local neural circuit of the mammalian brain. An in vitro hippocampal preparation …

Computational exploration of wave propagation and heating from transcranial focused ultrasound for neuromodulation

JK Mueller, L Ai, P Bansal… - Journal of neural …, 2016 - iopscience.iop.org
Objective. While ultrasound is largely established for use in diagnostic imaging, its
application for neuromodulation is relatively new and crudely understood. The objective of …