Development and evaluation of a flocked nasal midturbinate swab for self-collection in respiratory virus infection diagnostic testing

M Smieja, S Castriciano, S Carruthers… - Journal of clinical …, 2010 - Am Soc Microbiol
M Smieja, S Castriciano, S Carruthers, G So, S Chong, K Luinstra, JB Mahony, A Petrich…
Journal of clinical microbiology, 2010Am Soc Microbiol
We developed and evaluated flocked nasal midturbinate swabs obtained from 55
asymptomatic and 108 symptomatic volunteers. Self-collected swabs obtained from
asymptomatic volunteers yielded numbers of respiratory epithelial cells comparable to those
of staff-collected nasal (n= 55) or nasopharyngeal (n= 20) swabs. Specific viruses were
detected in swabs self-collected by 42/108 (38.9%) symptomatic volunteers by multiplex
PCR.
Abstract
We developed and evaluated flocked nasal midturbinate swabs obtained from 55 asymptomatic and 108 symptomatic volunteers. Self-collected swabs obtained from asymptomatic volunteers yielded numbers of respiratory epithelial cells comparable to those of staff-collected nasal (n = 55) or nasopharyngeal (n = 20) swabs. Specific viruses were detected in swabs self-collected by 42/108 (38.9%) symptomatic volunteers by multiplex PCR.
American Society for Microbiology