Characterization of the Bacteroides fragilis pathogenicity island in human blood culture isolates

MC Claros, ZC Claros, DW Hecht, DM Citron… - Anaerobe, 2006 - Elsevier
Bacteroides fragilis is an important anaerobic pathogen accounting for up to 10% of
bacteremias in adult patients. Enterotoxin producing B. fragilis (ETBF) strains have been
identified as enteric pathogens of children and adults. In order to further characterize the B.
fragilis pathogenicity island (BfPAI) and using PCR assays for bft-and mpII-metalloprotease
genes, we determined the frequency of B. fragilis strains with pattern I (containing the BfPAI
and its flanking region), pattern II (lacking both the BfPAI and the flanking region), and …