[HTML][HTML] De novo initiation of viral RNA-dependent RNA synthesis
CC Kao, P Singh, DJ Ecker - Virology, 2001 - Elsevier
CC Kao, P Singh, DJ Ecker
Virology, 2001•ElsevierRNA viruses use several initiation strategies to ensure that their RNAs are synthesized in
appropriate amounts, have correct termini, and can be translated efficiently. Many viruses
with genomes of single-stranded positive-, negative-, and double-stranded RNA initiate RNA
synthesis by a de novo (primer-independent) mechanism. This review summarizes
biochemical features and variations of de novo initiation in viral RNA replication.
appropriate amounts, have correct termini, and can be translated efficiently. Many viruses
with genomes of single-stranded positive-, negative-, and double-stranded RNA initiate RNA
synthesis by a de novo (primer-independent) mechanism. This review summarizes
biochemical features and variations of de novo initiation in viral RNA replication.
RNA viruses use several initiation strategies to ensure that their RNAs are synthesized in appropriate amounts, have correct termini, and can be translated efficiently. Many viruses with genomes of single-stranded positive-, negative-, and double-stranded RNA initiate RNA synthesis by a de novo (primer-independent) mechanism. This review summarizes biochemical features and variations of de novo initiation in viral RNA replication.
Elsevier