Variant in PNPLA3 is associated with alcoholic liver disease
C Tian, RP Stokowski, D Kershenobich, DG Ballinger… - Nature …, 2010 - nature.com
Two genome-wide association studies (GWAS) have described associations of variants in
PNPLA3 with nonalcoholic fatty liver and plasma liver enzyme levels. We investigated the …
PNPLA3 with nonalcoholic fatty liver and plasma liver enzyme levels. We investigated the …
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …
mood and anhedonia. Depression has a heritable component that has remained difficult to …
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …
[HTML][HTML] Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome-wide-…
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome-wide-…
A dynamic mapreduce scheduler for heterogeneous workloads
C Tian, H Zhou, Y He, L Zha - 2009 Eighth International …, 2009 - ieeexplore.ieee.org
MapReduce is an important programming model for building data centers containing ten of
thousands of nodes. In a practical data center of that scale, it is a common case that I/O-…
thousands of nodes. In a practical data center of that scale, it is a common case that I/O-…
Association of Systemic Lupus Erythematosus with C8orf13–BLK and ITGAM–ITGAX
Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in
which the risk of disease is influenced by complex genetic and environmental contributions. …
which the risk of disease is influenced by complex genetic and environmental contributions. …
TRAF1–C5 as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study
Background Rheumatoid arthritis has a complex mode of inheritance. Although HLA-DRB1
and PTPN22 are well-established susceptibility loci, other genes that confer a modest level …
and PTPN22 are well-established susceptibility loci, other genes that confer a modest level …
Characterizing the rate region of the (4, 3, 3) exact-repair regenerating codes
C Tian - IEEE Journal on Selected Areas in Communications, 2014 - ieeexplore.ieee.org
Exact-repair regenerating codes are considered for the case (n,k,d) = (4,3,3), for which a
complete characterization of the rate region is provided. This characterization answers in the …
complete characterization of the rate region is provided. This characterization answers in the …
Caching and delivery via interference elimination
We propose a new coded caching scheme where linear combinations of the file segments
are cached at the users, for the cases where the number of files is no greater than the number …
are cached at the users, for the cases where the number of files is no greater than the number …