exposure to relevant environmental experience is under strong genetic control. The subjects
for whom MRI scans were available partly overlapped with a sample of extended twin …

With the rapid advances in molecular biology, the near completion of the human genome,
the development of appropriate statistical genetic methods and the availability of the …

Despite a century of research on complex traits in humans, the relative importance and specific
nature of the influences of genes and environment on human traits remain controversial. …

Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts
for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying …

The power to detect sources of genetic and environmental variance varies with sample size,
study design, effect size and the statistical significance level chosen. We explored whether …

Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20
disease-associated genomic loci. Yet these only explain a small proportion of the genetic …

The degree to which individual variation in brain structure in humans is genetically or
environmentally determined is as yet not well understood. We studied the brains of 54 monozygotic …

A main challenge in genome-wide association studies (GWAS) is to pinpoint possible causal
variants. Results from GWAS typically do not directly translate into causal variants because …

Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

Background. Subjective well-being (SWB) can be partitioned into the components life satisfaction
and affect. Research on factors influencing these components of well-being has mainly …