User profiles for Enrique Castelao
![]() | Enrique Castelaopsychologue, CHUV, Lausanne, Suisse Verified email at chuv.ch Cited by 8657 |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Meta-analysis of genome-wide association studies of anxiety disorders
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study
Importance Most previous genome-wide association studies (GWAS) of depression have used
data from individuals of European descent. This limits the understanding of the underlying …
data from individuals of European descent. This limits the understanding of the underlying …
Determinants of the development of post-traumatic stress disorder, in the general population
M Perrin, CL Vandeleur, E Castelao, S Rothen… - Social psychiatry and …, 2014 - Springer
Purpose To assess (1) the lifetime prevalence of exposure both to trauma and post-traumatic
stress disorder (PTSD); (2) the risk of PTSD by type of trauma; and (3) the determinants of …
stress disorder (PTSD); (2) the risk of PTSD by type of trauma; and (3) the determinants of …
[HTML][HTML] Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors
…, M Budde, EM Byrne, W Cahn, M Casas, E Castelao… - Biological …, 2022 - Elsevier
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic …
which occur far more frequently, are a major source of disability and social and economic …
[HTML][HTML] Genome-wide association for major depression through age at onset stratification: major depressive disorder working group of the psychiatric genomics …
Background Major depressive disorder (MDD) is a disabling mood disorder, and despite a
known heritable component, a large meta-analysis of genome-wide association studies …
known heritable component, a large meta-analysis of genome-wide association studies …
Major depressive disorder working group of the psychiatric genomics consortium
A phenome-wide association and Mendelian Randomisation study of polygenic risk for
depression in UK Biobank - Ethnographic studies in innovative learning contexts Topic …
depression in UK Biobank - Ethnographic studies in innovative learning contexts Topic …
GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors
…, EM Byrne, W Cahn, E Castelao… - American journal of …, 2023 - Am Psychiatric Assoc
Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale
genome-wide association studies (GWASs) recently discovered and cross-validated …
genome-wide association studies (GWASs) recently discovered and cross-validated …
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls
Background Mood disorders (including major depressive disorder and bipolar disorder)
affect 10% to 20% of the population. They range from brief, mild episodes to severe, …
affect 10% to 20% of the population. They range from brief, mild episodes to severe, …
Prevalence and correlates of DSM-5 major depressive and related disorders in the community
CL Vandeleur, S Fassassi, E Castelao, J Glaus… - Psychiatry …, 2017 - Elsevier
Although the DSM-5 has suggested the two new categories of Persistent Depressive Disorders
(PDD) and Other Specified Depressive Disorders (OSDD), no study so far has applied …
(PDD) and Other Specified Depressive Disorders (OSDD), no study so far has applied …