User profiles for Jouke-Jan Hottenga
Jouke- Jan HottengaSenior Researcher, Vrije Universiteit Amsterdam Verified email at vu.nl Cited by 95954 |
Genome-wide association study identifies 74 loci associated with educational attainment
…, EG Holliday, G Homuth, MA Horan, JJ Hottenga… - Nature, 2016 - nature.com
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
…, TB Harris, JM Harris, EG Holliday, JJ Hottenga… - Nature …, 2016 - nature.com
Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
Variants in MTNR1B influence fasting glucose levels
To identify previously unknown genetic loci associated with fasting glucose concentrations,
we examined the leading association signals in ten genome-wide association scans …
we examined the leading association signals in ten genome-wide association scans …
The power of genetic diversity in genome-wide association studies of lipids
…, K Yoon, C Medina-Gomez, A Pitsillides, JJ Hottenga… - Nature, 2021 - nature.com
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use 1 . Despite …
prevalence worldwide owing to different dietary patterns and medication use 1 . Despite …
[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
…, M Hoogman, LE Hong, N Hosten, JJ Hottenga… - Brain imaging and …, 2014 - Springer
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …
collaborative network of researchers working together on a range of large-scale studies that …
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
…, C Hodgkinson, P Hoffmann, J Jan Hottenga… - Nature …, 2018 - nature.com
Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic
architecture or its genetic relationship with other disorders. To discover loci associated …
architecture or its genetic relationship with other disorders. To discover loci associated …
Genetic studies of body mass index yield new insights for obesity biology
…, Q Helmer, C Hengstenberg, O Holmen, JJ Hottenga… - Nature, 2015 - nature.com
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…
obesity better, here we conduct a genome-wide association study and Metabochip meta-…
Biological, clinical and population relevance of 95 loci for blood lipids
…, E Ingelsson, W Igl, G Kees Hovingh, JJ Hottenga… - Nature, 2010 - nature.com
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
…, NL Heard-Costa, V Hoesel, JJ Hottenga… - Nature …, 2010 - nature.com
Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …