SARS-CoV-2 501Y. V2 escapes neutralization by South African COVID-19 donor plasma

CK Wibmer, F Ayres, T Hermanus, M Madzivhandila… - Nature medicine, 2021 - nature.com
SARS-CoV-2 501Y.V2 (B.1.351), a novel lineage of coronavirus causing COVID-19, contains
substitutions in two immunodominant domains of the spike protein. Here, we show that …

Serotype distribution and invasive potential of group B streptococcus isolates causing disease in infants and colonizing maternal-newborn dyads

M Madzivhandila, PV Adrian, CL Cutland, L Kuwanda… - PloS one, 2011 - journals.plos.org
Background Serotype-specific polysaccharide based group B streptococcus (GBS) vaccines
are being developed. An understanding of the serotype epidemiology associated with …

Cross-reactive neutralizing antibody responses elicited by SARS-CoV-2 501Y. V2 (B. 1.351)

T Moyo-Gwete, M Madzivhandila… - … England Journal of …, 2021 - Mass Medical Soc
Mashudu Madzivhandila, Ph.D. … https://orcid.org/0000-0002-4269-9281, Mashudu
Madzivhandila, Ph.D. , Zanele … Moyo-Gwete and Madzivhandila contributed equally to this letter. …

[HTML][HTML] SARS-CoV-2 501Y. V2 (B. 1.351) elicits cross-reactive neutralizing antibodies

T Moyo-Gwete, M Madzivhandila, Z Makhado, F Ayres… - bioRxiv, 2021 - ncbi.nlm.nih.gov
Neutralization escape by SARS-CoV-2 variants, as has been observed in the 501Y. V2 (B.
1.351) variant, has impacted the efficacy of first generation COVID-19 vaccines. Here, the …

Distribution of pilus islands of group B streptococcus associated with maternal colonization and invasive disease in South Africa

M Madzivhandila, PV Adrian… - Journal of medical …, 2013 - microbiologyresearch.org
Group B streptococcus (GBS) is a leading cause of neonatal sepsis. Sortase-dependent
pilus-like structures have been identified on the surface of GBS, and have been found to be …

Shared N417-dependent epitope on the SARS-CoV-2 omicron, beta, and delta plus variants

T Moyo-Gwete, M Madzivhandila, NN Mkhize… - Journal of …, 2022 - Am Soc Microbiol
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve,
several variants of concern (VOCs) have arisen which are defined by multiple mutations in their …

[HTML][HTML] Comparing the immune abnormalities in MIS-C to healthy children and those with inflammatory disease reveals distinct inflammatory cytokine production and …

…, Z Makhado, SR Balla, M Madzivhandila… - Clinical …, 2024 - Elsevier
Multisystem inflammatory syndrome in children (MIS-C) is a severe, hyperinflammatory
disease that occurs after exposure to severe acute respiratory syndrome coronavirus 2 (SARS-…

HIV and risk of cardiovascular disease in sub-Saharan Africa: Rationale and design of the Ndlovu Cohort Study

…, S Aitken, M Madzivhandila… - European journal of …, 2017 - journals.sagepub.com
Background The largest proportion of people living with HIV resides in sub-Saharan Africa (SSA).
Evidence from developed countries suggests that HIV infection increases the relative …

Serotype, pilus island distribution and molecular epidemiology of Streptococcus agalactiae isolates from colonization and invasive disease

M Madzivhandila - 2013 - wiredspace.wits.ac.za
Background: Group B streptococcus (GBS) is a leading cause of invasive bacterial disease
in neonates. The possibility of maternal immunization with GBS-vaccines is being explored. …

Case report: mechanisms of HIV elite control in two African women

…, V Ramsuran, R Singh, M Madzivhandila… - BMC infectious …, 2018 - Springer
Background The majority of people living with HIV require antiretroviral therapy (ART) for
controlling viral replication, however there are rare HIV controllers who spontaneously and …