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Immune checkpoint targets are critical in regulating immune responses and have become pivotal in the development of immunotherapies for cancer and other diseases.
Immune cell surface markers are essential tools for identifying and classifying immune cells, widely used in immune monitoring and therapeutic research. They are employed clinically to diagnose blood disorders, assess immune status, and develop targeted immunotherapies.
Tumor-associated antigens (TAAs) are proteins or molecules expressed on the surface of tumor cells or secreted into the bloodstream that can be targeted for cancer diagnosis and therapy.
Cytokine receptor-targeted drugs are actively being developed for treating various conditions, including cancers, autoimmune diseases, and inflammatory disorders, with several agents already in clinical use or undergoing trials.
G-protein coupled Receptors (GPCRs) are key drug targets for various diseases, including cardiovascular, metabolic, and neurological disorders.
Other Cell Surface Receptors encompass various targets involved in various physiological and pathological processes, including immune response, cell adhesion, and signaling pathways.
Tyrosine kinases are critical enzymes that regulate cell growth and signaling, making them key targets for therapeutic intervention in cancer and other diseases.
Cell cycle regulatory enzymes are essential for controlling cell division and progression.
Protein modification enzymes regulate cellular processes through post-translational modifications, affecting protein function and stability.
Metabolic enzymes are involved in various biochemical processes that regulate metabolism and energy production.
Other enzymes include a diverse range of proteins involved in various physiological processes and disease mechanisms, with roles in immune response, blood coagulation, metabolism, and cellular stress.
Transcription factors regulate gene expression by binding to specific DNA sequences, influencing cellular processes such as growth, differentiation, and response to environmental stimuli.
Ion channels facilitate the flow of ions across cellular membranes, crucial for processes like signal transmission, muscle contraction, and cellular homeostasis.
Cytokines and growth factors are signaling molecules that mediate communication between cells, influencing immune responses, cell growth, differentiation, and repair processes.
Other targets include a diverse range of proteins and molecules involved in various biological processes such as signaling, metabolism, stress responses, and cell structure.
