product summary
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company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-SOD2/MnSOD antibody
catalog :
ab13533
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs, chicken
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 39
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:5000; loading ...; fig 1a
Foliaki S, Race B, Williams K, Baune C, Groveman B, Haigh C. Reduced SOD2 expression does not influence prion disease course or pathology in mice. PLoS ONE. 2021;16:e0259597 pubmed publisher
  • western blot; mouse; 1:1000; fig 5c
Che H, Li J, Li Y, Ma C, Liu H, Qin J, et al. p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 6c
  • western blot; mouse; loading ...; fig 3e, 5e
Gao J, Yuan J, Wang Q, Lei T, Shen X, Cui B, et al. Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2. Redox Biol. 2020;28:101345 pubmed publisher
  • western blot; rat; 1:5000; loading ...; fig 2b
Günther M, Al Nimer F, Piehl F, Risling M, Mathiesen T. Susceptibility to Oxidative Stress Is Determined by Genetic Background in Neuronal Cell Cultures. Eneuro. 2018;5: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2b
Song L, McMackin M, Nguyen A, Cortopassi G. Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism. Neurobiol Dis. 2017;100:30-38 pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Song L, Yu A, Murray K, Cortopassi G. Bipolar cell reduction precedes retinal ganglion neuron loss in a complex 1 knockout mouse model. Brain Res. 2017;1657:232-244 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 3a
  • western blot; mouse; 1:5000; fig 4a
Lauritzen K, Hasan Olive M, Regnell C, Kleppa L, Scheibye Knudsen M, Gjedde A, et al. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016;48:34-47 pubmed publisher
  • western blot; human; fig 5
Martinez L, Thames E, Kim J, Chaudhuri G, Singh R, Pervin S. Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis. BMC Cancer. 2016;16:559 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Jian Z, Liang B, Pan X, Xu G, Guo S, Li T, et al. CUEDC2 modulates cardiomyocyte oxidative capacity by regulating GPX1 stability. EMBO Mol Med. 2016;8:813-29 pubmed publisher
  • western blot; mouse; 1:2000; fig 3
Tweedie D, Fukui K, Li Y, Yu Q, Barak S, Tamargo I, et al. Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms. PLoS ONE. 2016;11:e0156493 pubmed publisher
  • western blot; human; 1:5000; fig 4
Chen W, Shaw L, Chang P, Tung S, Chang T, Shen C, et al. Hepatoprotective effect of resveratrol against ethanol-induced oxidative stress through induction of superoxide dismutase in vivo and in vitro. Exp Ther Med. 2016;11:1231-1238 pubmed
  • western blot; mouse; 1:1000; fig s1
Safdar A, Khrapko K, Flynn J, Saleem A, De Lisio M, Johnston A, et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle. 2016;6:7 pubmed publisher
Gratias P, Nasr J, Affortit C, Ceccato J, François F, Casas F, et al. Impulse Noise Induced Hidden Hearing Loss, Hair Cell Ciliary Changes and Oxidative Stress in Mice. Antioxidants (Basel). 2021;10: pubmed publisher
Lavier J, Beaumann M, Menétrey S, Bouzourene K, Rosenblatt Velin N, Pialoux V, et al. High-intensity exercise in hypoxia improves endothelial function via increased nitric oxide bioavailability in C57BL/6 mice. Acta Physiol (Oxf). 2021;233:e13700 pubmed publisher
Talarico M, Nunes R, Silva G, Costa L, Cardoso M, Esteves S, et al. High Expression of SOD2 Protein Is a Strong Prognostic Factor for Stage IIIB Squamous Cell Cervical Carcinoma. Antioxidants (Basel). 2021;10: pubmed publisher
Aleksic M, Kalezic A, Saso L, Jankovic A, Korac B, Korac A. The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism. Antioxidants (Basel). 2021;10: pubmed publisher
Thangaraj A, Chivero E, Tripathi A, Singh S, Niu F, Guo M, et al. HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress. Redox Biol. 2021;40:101843 pubmed publisher
Colasuonno F, Bertini E, Tartaglia M, Compagnucci C, Moreno S. Mitochondrial Abnormalities in Induced Pluripotent Stem Cells-Derived Motor Neurons from Patients with Riboflavin Transporter Deficiency. Antioxidants (Basel). 2020;9: pubmed publisher
Cui L, Jiang X, Zhang C, Li D, Yu S, Wan F, et al. Ketamine induces endoplasmic reticulum stress in rats and SV-HUC-1 human uroepithelial cells by activating NLRP3/TXNIP aix. Biosci Rep. 2019;39: pubmed publisher
Liu T, Han Y, Zhou T, Zhang R, Chen H, Chen S, et al. Mechanisms of ROS-induced mitochondria-dependent apoptosis underlying liquid storage of goat spermatozoa. Aging (Albany NY). 2019;11:7880-7898 pubmed publisher
Grossmann D, Berenguer Escuder C, Bellet M, Scheibner D, Bohler J, Massart F, et al. Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease. Antioxid Redox Signal. 2019;31:1213-1234 pubmed publisher
Hancock M, Hafstad A, Nabeebaccus A, Catibog N, Logan A, Smyrnias I, et al. Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. elife. 2018;7: pubmed publisher
Cummins N, Tweedie A, Zuryn S, Bertran Gonzalez J, Götz J. Disease-associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria. EMBO J. 2019;38: pubmed publisher
Li Z, Liu T, Ma J, Guo Q, Ma L, Lv Q, et al. TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure. Aging (Albany NY). 2018;10:3474-3485 pubmed publisher
Abuaita B, Schultz T, O Riordan M. Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus. Cell Host Microbe. 2018;24:625-636.e5 pubmed publisher
Jing R, Corbett J, Cai J, Beeson G, Beeson C, CHAN S, et al. A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome. Cell Rep. 2018;25:1469-1484.e5 pubmed publisher
Widdrington J, Gómez Durán A, Pyle A, Ruchaud Sparagano M, Scott J, Baudouin S, et al. Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses. Front Immunol. 2018;9:2217 pubmed publisher
Wen J, Garg N. Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease. PLoS Negl Trop Dis. 2018;12:e0006687 pubmed publisher
Shi Z, Li C, Yin Y, Yang Z, Xue H, Mu N, et al. Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction. Biomed Res Int. 2018;2018:2708491 pubmed publisher
Jeong B, Lee H, Park C, Kang J, Yu S, Choi D, et al. Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury. PLoS ONE. 2018;13:e0191034 pubmed publisher
Vereczki V, Mansour J, Pour Ghaz I, Bodnar I, Pintér O, Zelena D, et al. Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice. Mitochondrion. 2017;34:115-126 pubmed publisher
Biswal M, Han P, Zhu P, Wang Z, Li H, ILDEFONSO C, et al. Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD. Invest Ophthalmol Vis Sci. 2017;58:1237-1245 pubmed publisher
Chavan H, Christudoss P, Mickey K, Tessman R, Ni H, Swerdlow R, et al. Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response. Oxid Med Cell Longev. 2017;2017:9251303 pubmed publisher
Lee W, Higuchi H, Ikeda S, Macke E, Takimoto T, Pattnaik B, et al. Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. elife. 2016;5: pubmed publisher
Ren J, Zhang M, Li T, Zhang J, Lin R, Chen S, et al. Quantitative Proteomics of Sleep-Deprived Mouse Brains Reveals Global Changes in Mitochondrial Proteins. PLoS ONE. 2016;11:e0163500 pubmed publisher
Nguyen T, Caito S, Zackert W, West J, Zhu S, Aschner M, et al. Scavengers of reactive ?-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7. Aging (Albany NY). 2016;8:1759-80 pubmed publisher
Fisher Wellman K, Ryan T, Smith C, Gilliam L, Lin C, Reese L, et al. A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice. Diabetes. 2016;65:3249-3261 pubmed
Kim J, Fiesel F, Belmonte K, Hudec R, Wang W, Kim C, et al. miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1). Mol Neurodegener. 2016;11:55 pubmed publisher
Wang R, Yin C, Li X, Yang X, Yang Y, Zhang M, et al. Reduced SOD2 expression is associated with mortality of hepatocellular carcinoma patients in a mutant p53-dependent manner. Aging (Albany NY). 2016;8:1184-200 pubmed publisher
product information
CatalogNumber :
ab13533
ItemName :
Anti-SOD2/MnSOD antibody
Product Type :
Primary Antibodies
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Size :
50 µg
SpeciesSummary :
Chk, Cow, Dog, Gpig, Grb, Hm, Hu, Mk, Ms, Pig, Rat, Rb, Shp, Xl
Uses :
ELISA, ICC/IF, IHC-Fr, IHC-P, IP, WB
more info or order :
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK
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