This is a Validated Antibody Database (VAD) review about human BRCA1, based on 65 published articles (read how Labome selects the articles), using BRCA1 antibody in all methods. It is aimed to help Labome visitors find the most suited BRCA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
BRCA1 synonym: BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53
Knockout validation
Abcam |
| Abcam BRCA1 antibody (Abcam, ab131360) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi |
Abcam domestic rabbit polyclonal |
| Abcam BRCA1 antibody (Abcam, ab191042) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi |
Invitrogen mouse monoclonal (6B4) |
| In order to analyze telomere markers and alternative lengthening in BRCA1 defective cells, Invitrogen BRCA1 antibody (Thermo Fisher, MA1-23164) was used in immunocytochemistry on human samples at 1:400 (fig 6), in western blot on human samples at 1:1000 (fig 5), in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 6) and in western blot knockout validation on mouse samples at 1:1000 (fig 5). Genes Chromosomes Cancer (2016) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 5c) and in western blot on human samples (fig 6f). Int J Biol Sci (2022) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 2d) and in western blot on human samples (fig 4c). Nat Commun (2021) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in western blot on human samples at 1:100 (fig 5j). JCI Insight (2021) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples at 1:100 (fig 7f). Nat Struct Mol Biol (2020) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunohistochemistry on human samples (fig 2b) and in western blot on human samples (fig 2f). Cell Death Differ (2019) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, SC-6954) was used in western blot on human samples (fig 1h). Cell (2019) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples at 1:100 (fig 5i). Oncogene (2019) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (SantaCruz, sc-6954) was used in immunocytochemistry on human samples at 1:250 (fig s3b). Nat Commun (2018) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc6954) was used in western blot on human samples at 1:200 (fig 4d). Genome Biol (2018) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples (fig 3a). Mol Cell (2018) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (SantaCruz, sc-6954) was used in western blot on human samples (fig 2a). Tumour Biol (2017) ncbi |
mouse monoclonal (D-9) |
| In order to investigate the involvement of RNF8- and Ube2S-dependent ubiquitin lysine 11-linkage modification in the DNA damage response, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 4c). Mol Cell (2017) ncbi |
mouse monoclonal (D-9) |
| In order to test whether the attenuation of non-homologous end joining repair is sufficient to compromise homologous recombination in DEK knockout mice, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 4a). Sci Rep (2017) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa cruz, Sc6954) was used in immunocytochemistry on human samples (fig 6d) and in western blot on human samples (fig 7e). Genes Dev (2017) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples (fig 5a). J Cell Biol (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 3a) and in western blot on human samples (fig s1). Oncotarget (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples at 1:1000 (fig 5). J Cell Sci (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples (fig 2). PLoS ONE (2016) ncbi |
mouse monoclonal |
| In order to describe how a CHK1 inhibitor reduces the growth of radioresistant breast cancer cells, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2e). Oncotarget (2016) ncbi |
mouse monoclonal (D-9) |
| In order to describe how a CHK1 inhibitor reduces the growth of radioresistant breast cancer cells, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2e). Oncotarget (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples (fig s2). PLoS Genet (2016) ncbi |
mouse monoclonal (D-9) |
| In order to investigate the role of topoisomerase IIbeta-binding protein 1 in DNA repair and its contribution to cancer, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 3). J Cell Biol (2016) ncbi |
mouse monoclonal (D-9) |
| In order to report that the RAP80-binding partner TRAIP regulates recruitment of the damage signaling machinery and promotes homologous recombination, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, 6954) was used in immunocytochemistry on human samples at 1:400 (fig 4). Nat Commun (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc6954) was used in immunocytochemistry on human samples (fig 4). Cell Cycle (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples . Nature (2015) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig s10). PLoS Genet (2015) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples (fig 4). Cell Death Dis (2015) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in immunoprecipitation on human samples (fig 1b). Oncogene (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on mouse samples (fig 3b). Mol Cell Biol (2015) ncbi |
mouse monoclonal |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2a). Oncogene (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2a). Oncogene (2016) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 4). PLoS ONE (2015) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Novus, sc-6954) was used in western blot on human samples at 1:50 (fig 2). PLoS ONE (2015) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa, sc-6954) was used in immunocytochemistry on human samples (fig 2a). Genes Dev (2014) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in western blot on human samples at 1:500 (fig 5). DNA Repair (Amst) (2015) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunohistochemistry - paraffin section on human samples , in immunoprecipitation on human samples and in western blot on human samples . Cancer Res (2015) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in chromatin immunoprecipitation on human samples (fig 7) and in western blot on human samples (fig 1). Oncotarget (2014) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa, sc-6954) was used in immunocytochemistry on human samples . elife (2014) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Technology, sc-6954) was used in immunocytochemistry on human samples and in western blot on human samples . Mol Cancer (2014) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa, sc-6954) was used in western blot on human samples . Mol Cell (2014) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples . Nucleic Acids Res (2014) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples and in western blot on human samples . PLoS ONE (2012) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples . PLoS ONE (2012) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in western blot on human samples . Genes Cells (2012) ncbi |
mouse monoclonal (D-9) |
| Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on rhesus macaque samples (fig 3). J Virol (2010) ncbi |
Abcam
domestic rabbit polyclonal |
| Abcam BRCA1 antibody (Abcam, ab191042) was used in western blot on rat samples (fig 3b). Redox Biol (2022) ncbi |
domestic rabbit polyclonal |
| Abcam BRCA1 antibody (Abcam, ab238983) was used in western blot on human samples at 1:1000 (fig 1j, 1k). Front Pharmacol (2021) ncbi |
mouse monoclonal (MS110) |
| Abcam BRCA1 antibody (Abcam, MS110) was used in immunocytochemistry on human samples (fig 1a) and in western blot on human samples (fig 3a). Nucleic Acids Res (2019) ncbi |
mouse monoclonal (MS110) |
| Abcam BRCA1 antibody (Abcam, ab16780) was used in immunohistochemistry on human samples (fig 8d). Cell Death Differ (2019) ncbi |
domestic rabbit polyclonal |
| Abcam BRCA1 antibody (Abcam, ab191042) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi |
| Abcam BRCA1 antibody (Abcam, ab131360) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi | |
domestic rabbit polyclonal |
| Abcam BRCA1 antibody (Abcam, ab191042) was used in immunohistochemistry on rat samples at 1:50 (fig 4a). Sci Rep (2016) ncbi |
domestic rabbit polyclonal |
| Abcam BRCA1 antibody (Abcam, ab191042) was used in immunocytochemistry on mouse samples (fig 7). BMC Mol Biol (2016) ncbi |
| Abcam BRCA1 antibody (Abcam, ab131360) was used in western blot on human samples (fig 1). Biochem J (2016) ncbi |
Invitrogen
domestic rabbit polyclonal |
| Invitrogen BRCA1 antibody (Invitrogen, PA5-97358) was used in western blot on rat samples (fig 3b). Redox Biol (2022) ncbi |
mouse monoclonal (17F8) |
| Invitrogen BRCA1 antibody (Thermo Fisher Scientific, 17F8) was used in ChIP-Seq on mouse samples (fig 4a). elife (2018) ncbi |
mouse monoclonal (MS110) |
| Invitrogen BRCA1 antibody (Thermo Fisher Scientific, MA1-137) was used in western blot on human samples (fig s3i). Nature (2017) ncbi |
mouse monoclonal (6B4) |
| In order to analyze telomere markers and alternative lengthening in BRCA1 defective cells, Invitrogen BRCA1 antibody (Thermo Fisher, MA1-23164) was used in immunocytochemistry on human samples at 1:400 (fig 6), in western blot on human samples at 1:1000 (fig 5), in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 6) and in western blot knockout validation on mouse samples at 1:1000 (fig 5). Genes Chromosomes Cancer (2016) ncbi |
mouse monoclonal (MS110) |
| In order to assess the functionality of BRCA1 in the heterozygous state, Invitrogen BRCA1 antibody (Thermo, MS110) was used in western blot on human samples at 1:1000 (fig s2b). Nat Commun (2014) ncbi |
Cell Signaling Technology
domestic rabbit polyclonal |
| Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010) was used in western blot on human samples at 1:1000 (fig s4f). Nat Commun (2022) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology BRCA1 antibody (CST, 9009T) was used in western blot on mouse samples (fig 5b, 5c). Front Pharmacol (2021) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology BRCA1 antibody (Cell Signaling Technology, #9010) was used in western blot on human samples (fig 1a). Sci Rep (2021) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010S) was used in western blot on human samples at 1:1000 (fig 5h). Nat Commun (2020) ncbi |
domestic rabbit polyclonal |
| In order to determine that HPV activates the Fanconi anemia pathway, leading to the accumulation of a key regulatory protein, FANCD2, in large nuclear foci, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010) was used in western blot on human samples (fig 4a). MBio (2017) ncbi |
domestic rabbit monoclonal (D54A8) |
| In order to elucidate a mutually regulatory relationship between signal transducer and activator of transcription 5 and nucleophosmin, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9025) was used in western blot on human samples (fig 5). Cell Death Dis (2016) ncbi |
domestic rabbit polyclonal |
| In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9009) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010) was used in western blot on human samples at 1:1000 (fig 3b). Aging (Albany NY) (2016) ncbi |
domestic rabbit polyclonal |
| In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9009) was used in immunohistochemistry - paraffin section on human samples at 1:25 (fig s1). BMC Cancer (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology BRCA1 antibody (Cell signaling Technology, 9009) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2016) ncbi |
Articles Reviewed
- Pickholtz I, Saadyan S, Keshet G, Wang V, Cohen R, Bouwman P, et al. Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells. Oncotarget. 2014;5:11827-46 pubmed
articles
contribute
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
questions and comments