This is a Validated Antibody Database (VAD) review about human BRCA1, based on 65 published articles (read how Labome selects the articles), using BRCA1 antibody in all methods. It is aimed to help Labome visitors find the most suited BRCA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
BRCA1 synonym: BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53

Knockout validation
Abcam
  • western blot knockout validation; human; fig s2
Abcam BRCA1 antibody (Abcam, ab131360) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; human; fig s2
Abcam BRCA1 antibody (Abcam, ab191042) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi
Invitrogen
mouse monoclonal (6B4)
  • immunocytochemistry; human; 1:400; fig 6
  • western blot; human; 1:1000; fig 5
  • immunocytochemistry knockout validation; mouse; 1:400; fig 6
  • western blot knockout validation; mouse; 1:1000; fig 5
In order to analyze telomere markers and alternative lengthening in BRCA1 defective cells, Invitrogen BRCA1 antibody (Thermo Fisher, MA1-23164) was used in immunocytochemistry on human samples at 1:400 (fig 6), in western blot on human samples at 1:1000 (fig 5), in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 6) and in western blot knockout validation on mouse samples at 1:1000 (fig 5). Genes Chromosomes Cancer (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig 5c
  • western blot; human; loading ...; fig 6f
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 5c) and in western blot on human samples (fig 6f). Int J Biol Sci (2022) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; loading ...; fig 2d
  • western blot; human; loading ...; fig 4c
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 2d) and in western blot on human samples (fig 4c). Nat Commun (2021) ncbi
mouse monoclonal (D-9)
  • western blot; human; 1:100; loading ...; fig 5j
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in western blot on human samples at 1:100 (fig 5j). JCI Insight (2021) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; 1:100; loading ...; fig 7f
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples at 1:100 (fig 7f). Nat Struct Mol Biol (2020) ncbi
mouse monoclonal (D-9)
  • immunohistochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 2f
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunohistochemistry on human samples (fig 2b) and in western blot on human samples (fig 2f). Cell Death Differ (2019) ncbi
mouse monoclonal (D-9)
  • western blot; human; loading ...; fig 1h
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, SC-6954) was used in western blot on human samples (fig 1h). Cell (2019) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; 1:100; loading ...; fig 5i
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples at 1:100 (fig 5i). Oncogene (2019) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; 1:250; loading ...; fig s3b
Santa Cruz Biotechnology BRCA1 antibody (SantaCruz, sc-6954) was used in immunocytochemistry on human samples at 1:250 (fig s3b). Nat Commun (2018) ncbi
mouse monoclonal (D-9)
  • western blot; human; 1:200; fig 4d
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc6954) was used in western blot on human samples at 1:200 (fig 4d). Genome Biol (2018) ncbi
mouse monoclonal (D-9)
  • western blot; human; fig 3a
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples (fig 3a). Mol Cell (2018) ncbi
mouse monoclonal (D-9)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology BRCA1 antibody (SantaCruz, sc-6954) was used in western blot on human samples (fig 2a). Tumour Biol (2017) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; loading ...; fig 4c
In order to investigate the involvement of RNF8- and Ube2S-dependent ubiquitin lysine 11-linkage modification in the DNA damage response, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 4c). Mol Cell (2017) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; loading ...; fig 4a
In order to test whether the attenuation of non-homologous end joining repair is sufficient to compromise homologous recombination in DEK knockout mice, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 4a). Sci Rep (2017) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; loading ...; fig 6d
  • western blot; human; loading ...; fig 7e
Santa Cruz Biotechnology BRCA1 antibody (Santa cruz, Sc6954) was used in immunocytochemistry on human samples (fig 6d) and in western blot on human samples (fig 7e). Genes Dev (2017) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; loading ...; fig 5a
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples (fig 5a). J Cell Biol (2016) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; loading ...; fig 3a
  • western blot; human; loading ...; fig s1
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 3a) and in western blot on human samples (fig s1). Oncotarget (2016) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; 1:1000; fig 5
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples at 1:1000 (fig 5). J Cell Sci (2016) ncbi
mouse monoclonal (D-9)
  • western blot; human; fig 2
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples (fig 2). PLoS ONE (2016) ncbi
mouse monoclonal
  • western blot; human; 1:200; loading ...; fig 2e
In order to describe how a CHK1 inhibitor reduces the growth of radioresistant breast cancer cells, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2e). Oncotarget (2016) ncbi
mouse monoclonal (D-9)
  • western blot; human; 1:200; loading ...; fig 2e
In order to describe how a CHK1 inhibitor reduces the growth of radioresistant breast cancer cells, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2e). Oncotarget (2016) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig s2
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples (fig s2). PLoS Genet (2016) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig 3
In order to investigate the role of topoisomerase IIbeta-binding protein 1 in DNA repair and its contribution to cancer, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 3). J Cell Biol (2016) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; 1:400; fig 4
In order to report that the RAP80-binding partner TRAIP regulates recruitment of the damage signaling machinery and promotes homologous recombination, Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, 6954) was used in immunocytochemistry on human samples at 1:400 (fig 4). Nat Commun (2016) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig 4
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc6954) was used in immunocytochemistry on human samples (fig 4). Cell Cycle (2016) ncbi
mouse monoclonal (D-9)
  • western blot; human
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples . Nature (2015) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig s10
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig s10). PLoS Genet (2015) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig 4
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples (fig 4). Cell Death Dis (2015) ncbi
mouse monoclonal (D-9)
  • immunoprecipitation; human; fig 1b
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in immunoprecipitation on human samples (fig 1b). Oncogene (2016) ncbi
mouse monoclonal (D-9)
  • western blot; mouse; fig 3b
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on mouse samples (fig 3b). Mol Cell Biol (2015) ncbi
mouse monoclonal
  • western blot; human; 1:200; loading ...; fig 2a
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2a). Oncogene (2016) ncbi
mouse monoclonal (D-9)
  • western blot; human; 1:200; loading ...; fig 2a
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on human samples at 1:200 (fig 2a). Oncogene (2016) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig 4
Santa Cruz Biotechnology BRCA1 antibody (santa Cruz, sc-6954) was used in immunocytochemistry on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (D-9)
  • western blot; human; 1:50; fig 2
Santa Cruz Biotechnology BRCA1 antibody (Novus, sc-6954) was used in western blot on human samples at 1:50 (fig 2). PLoS ONE (2015) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human; fig 2a
Santa Cruz Biotechnology BRCA1 antibody (Santa, sc-6954) was used in immunocytochemistry on human samples (fig 2a). Genes Dev (2014) ncbi
mouse monoclonal (D-9)
  • western blot; human; 1:500; fig 5
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in western blot on human samples at 1:500 (fig 5). DNA Repair (Amst) (2015) ncbi
mouse monoclonal (D-9)
  • immunohistochemistry - paraffin section; human
  • immunoprecipitation; human
  • western blot; human
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunohistochemistry - paraffin section on human samples , in immunoprecipitation on human samples and in western blot on human samples . Cancer Res (2015) ncbi
mouse monoclonal (D-9)
  • chromatin immunoprecipitation; human; fig 7
  • western blot; human; fig 1
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in chromatin immunoprecipitation on human samples (fig 7) and in western blot on human samples (fig 1). Oncotarget (2014) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human
Santa Cruz Biotechnology BRCA1 antibody (Santa, sc-6954) was used in immunocytochemistry on human samples . elife (2014) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human
  • western blot; human
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Technology, sc-6954) was used in immunocytochemistry on human samples and in western blot on human samples . Mol Cancer (2014) ncbi
mouse monoclonal (D-9)
  • western blot; human
Santa Cruz Biotechnology BRCA1 antibody (Santa, sc-6954) was used in western blot on human samples . Mol Cell (2014) ncbi
mouse monoclonal (D-9)
  • western blot; human
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in western blot on human samples . Nucleic Acids Res (2014) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human
  • western blot; human
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in immunocytochemistry on human samples and in western blot on human samples . PLoS ONE (2012) ncbi
mouse monoclonal (D-9)
  • immunocytochemistry; human
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, sc-6954) was used in immunocytochemistry on human samples . PLoS ONE (2012) ncbi
mouse monoclonal (D-9)
  • western blot; human
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz Biotechnology, sc-6954) was used in western blot on human samples . Genes Cells (2012) ncbi
mouse monoclonal (D-9)
  • western blot; rhesus macaque; fig 3
Santa Cruz Biotechnology BRCA1 antibody (Santa Cruz, D-9) was used in western blot on rhesus macaque samples (fig 3). J Virol (2010) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 3b
Abcam BRCA1 antibody (Abcam, ab191042) was used in western blot on rat samples (fig 3b). Redox Biol (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1j, 1k
Abcam BRCA1 antibody (Abcam, ab238983) was used in western blot on human samples at 1:1000 (fig 1j, 1k). Front Pharmacol (2021) ncbi
mouse monoclonal (MS110)
  • immunocytochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 3a
Abcam BRCA1 antibody (Abcam, MS110) was used in immunocytochemistry on human samples (fig 1a) and in western blot on human samples (fig 3a). Nucleic Acids Res (2019) ncbi
mouse monoclonal (MS110)
  • immunohistochemistry; human; loading ...; fig 8d
Abcam BRCA1 antibody (Abcam, ab16780) was used in immunohistochemistry on human samples (fig 8d). Cell Death Differ (2019) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; fig s2
Abcam BRCA1 antibody (Abcam, ab191042) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi
  • western blot knockout validation; human; fig s2
Abcam BRCA1 antibody (Abcam, ab131360) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:50; loading ...; fig 4a
Abcam BRCA1 antibody (Abcam, ab191042) was used in immunohistochemistry on rat samples at 1:50 (fig 4a). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; fig 7
Abcam BRCA1 antibody (Abcam, ab191042) was used in immunocytochemistry on mouse samples (fig 7). BMC Mol Biol (2016) ncbi
  • western blot; human; fig 1
Abcam BRCA1 antibody (Abcam, ab131360) was used in western blot on human samples (fig 1). Biochem J (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 3b
Invitrogen BRCA1 antibody (Invitrogen, PA5-97358) was used in western blot on rat samples (fig 3b). Redox Biol (2022) ncbi
mouse monoclonal (17F8)
  • ChIP-Seq; mouse; loading ...; fig 4a
Invitrogen BRCA1 antibody (Thermo Fisher Scientific, 17F8) was used in ChIP-Seq on mouse samples (fig 4a). elife (2018) ncbi
mouse monoclonal (MS110)
  • western blot; human; loading ...; fig s3i
Invitrogen BRCA1 antibody (Thermo Fisher Scientific, MA1-137) was used in western blot on human samples (fig s3i). Nature (2017) ncbi
mouse monoclonal (6B4)
  • immunocytochemistry; human; 1:400; fig 6
  • western blot; human; 1:1000; fig 5
  • immunocytochemistry knockout validation; mouse; 1:400; fig 6
  • western blot knockout validation; mouse; 1:1000; fig 5
In order to analyze telomere markers and alternative lengthening in BRCA1 defective cells, Invitrogen BRCA1 antibody (Thermo Fisher, MA1-23164) was used in immunocytochemistry on human samples at 1:400 (fig 6), in western blot on human samples at 1:1000 (fig 5), in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 6) and in western blot knockout validation on mouse samples at 1:1000 (fig 5). Genes Chromosomes Cancer (2016) ncbi
mouse monoclonal (MS110)
  • western blot; human; 1:1000; fig s2b
In order to assess the functionality of BRCA1 in the heterozygous state, Invitrogen BRCA1 antibody (Thermo, MS110) was used in western blot on human samples at 1:1000 (fig s2b). Nat Commun (2014) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s4f
Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010) was used in western blot on human samples at 1:1000 (fig s4f). Nat Commun (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5b, 5c
Cell Signaling Technology BRCA1 antibody (CST, 9009T) was used in western blot on mouse samples (fig 5b, 5c). Front Pharmacol (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology BRCA1 antibody (Cell Signaling Technology, #9010) was used in western blot on human samples (fig 1a). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5h
Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010S) was used in western blot on human samples at 1:1000 (fig 5h). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4a
In order to determine that HPV activates the Fanconi anemia pathway, leading to the accumulation of a key regulatory protein, FANCD2, in large nuclear foci, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010) was used in western blot on human samples (fig 4a). MBio (2017) ncbi
domestic rabbit monoclonal (D54A8)
  • western blot; human; loading ...; fig 5
In order to elucidate a mutually regulatory relationship between signal transducer and activator of transcription 5 and nucleophosmin, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9025) was used in western blot on human samples (fig 5). Cell Death Dis (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9009) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9010) was used in western blot on human samples at 1:1000 (fig 3b). Aging (Albany NY) (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:25; fig s1
In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Cell Signaling Technology BRCA1 antibody (Cell Signaling, 9009) was used in immunohistochemistry - paraffin section on human samples at 1:25 (fig s1). BMC Cancer (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 6a
Cell Signaling Technology BRCA1 antibody (Cell signaling Technology, 9009) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2016) ncbi
Articles Reviewed
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  2. Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, et al. BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance. Redox Biol. 2022;54:102356 pubmed publisher
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