This is a Validated Antibody Database (VAD) review about human TDP 43, based on 27 published articles (read how Labome selects the articles), using TDP 43 antibody in all methods. It is aimed to help Labome visitors find the most suited TDP 43 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TDP 43 synonym: ALS10; TDP-43
Abnova
mouse monoclonal (2E2-D3) |
| Abnova TDP 43 antibody (Abnova, H00023435-M01) was used in immunocytochemistry on human samples at 1:500 (fig 3). Acta Neuropathol Commun (2020) ncbi |
mouse monoclonal (2E2-D3) |
| In order to investigate the involvement of HspBP1 in the neuronal susceptibility towards misfolded proteins, Abnova TDP 43 antibody (Abnova, H00023435-M01) was used in western blot on mouse samples (fig 4a). Proc Natl Acad Sci U S A (2017) ncbi |
mouse monoclonal (2E2-D3) |
| In order to examine the mutation spectrum of the TANK-Binding Kinase 1 gene and its associated phenotypic spectrum in patients with FTD, ALS or FTD plus ALS, Abnova TDP 43 antibody (Abnova, 2E2-D3) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 3a). Hum Mutat (2017) ncbi |
mouse monoclonal (2E2-D3) |
| Abnova TDP 43 antibody (ABNOVA, H00023435-M01) was used in immunohistochemistry on fruit fly |
mouse monoclonal (2E2-D3) |
| In order to detail the neuropathological features of the anti-IgLON5 syndrome in order to diagnose patients, Abnova TDP 43 antibody (Abnova, 2E2-D3) was used in immunohistochemistry - paraffin section on human samples at 1:500. Acta Neuropathol (2016) ncbi |
mouse monoclonal (2E2-D3) |
| In order to determine the subcellular localization of TDP-43 in circulating lymphomonocytes and in the constituent cells of patients with various ALS-linked mutant genes, Abnova TDP 43 antibody (Abnova, H00023435-M01) was used in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 2a). Neuropathol Appl Neurobiol (2017) ncbi |
mouse monoclonal (2E2-D3) |
| Abnova TDP 43 antibody (Abnova, H00023435-M01) was used in western blot on mouse samples (fig 3c). Nat Commun (2016) ncbi |
mouse monoclonal (2E2-D3) |
| Abnova TDP 43 antibody (Abnova, 2E2-D3) was used in immunocytochemistry on human samples at 1:1000 and in western blot on human samples at 1:2000. J Biol Chem (2014) ncbi |
mouse monoclonal (2E2-D3) |
| In order to investigate the role of repressor element 1-silencing transcription factor in neurodegeneration during ageing, Abnova TDP 43 antibody (Abnova, H00023435-M01) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5). Nature (2014) ncbi |
mouse monoclonal (2E2-D3) |
| Abnova TDP 43 antibody (Abnova , H00023435-M01) was used in western blot on human samples (fig 1). Biochim Biophys Acta (2014) ncbi |
Abcam
domestic rabbit monoclonal (EPR5810) |
| Abcam TDP 43 antibody (Abcam, ab109535) was used in immunohistochemistry on mouse samples at 1:500 (fig 1a) and in western blot on mouse samples (fig 4f). Nat Commun (2020) ncbi |
mouse monoclonal (2E2-D3) |
| Abcam TDP 43 antibody (Abcam, ab57105) was used in western blot on roundworm |
domestic rabbit monoclonal |
| Abcam TDP 43 antibody (Abcam, Ab133547) was used in western blot on mouse samples at 1:10,000 (fig s4g). Nat Commun (2018) ncbi |
mouse monoclonal (2E2-D3) |
| In order to research the effects of two familial ALS proteins on DNA damage repair, Abcam TDP 43 antibody (Abcam, ab57105) was used in immunohistochemistry on human samples (fig 3a). Proc Natl Acad Sci U S A (2016) ncbi |
mouse monoclonal (2E2-D3) |
| In order to characterize the role of endolysosomes in skeletal muscle pathology observed in a model of Alzheimer's disease with a cholesterol-fed rabbit, Abcam TDP 43 antibody (Abcam, ab57105) was used in immunohistochemistry - frozen section on domestic rabbit samples (fig s1). Front Aging Neurosci (2016) ncbi |
domestic rabbit polyclonal |
| In order to study cytosolic localization of Fox proteins in motor neurons of G93A SOD1 mice, Abcam TDP 43 antibody (Abcam, ab41881) was used in immunohistochemistry - free floating section on mouse samples at 1:200 (fig 4b). Histochem Cell Biol (2016) ncbi |
BioLegend
rat monoclonal (1D3/TDP-43) |
| BioLegend TDP 43 antibody (BioLegend, 829901) was used in western blot on mouse samples (fig 3a). Cell Rep (2021) ncbi |
rat monoclonal (1D3/TDP-43) |
| BioLegend TDP 43 antibody (Biolegend, 829901) was used in immunocytochemistry on human samples at 1:500 (fig 7e) and in western blot on human samples at 1:500 (fig s5a). Neuron (2019) ncbi |
R&D Systems
mouse monoclonal (671834) |
| R&D Systems TDP 43 antibody (Bio techne, MAB7778) was used in western blot on mouse samples at 1:1000 (fig 5d). iScience (2021) ncbi |
Novus Biologicals
domestic rabbit polyclonal |
| Novus Biologicals TDP 43 antibody (Novus Biologicals, NB110-55376) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 5a). Dis Model Mech (2017) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (41-7.1) |
| In order to show that upregulation of HSPB8 attenuates TDP-43 fragment-mediated toxicity, Santa Cruz Biotechnology TDP 43 antibody (Santa Cruz, sc-100871) was used in western blot on human samples (fig 5b). Hum Mol Genet (2016) ncbi |
Cell Signaling Technology
domestic rabbit polyclonal |
| Cell Signaling Technology TDP 43 antibody (Cell signaling, 3448) was used in immunocytochemistry on human samples (fig 6d). Ann Neurol (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology TDP 43 antibody (Cell Signaling, 3449S) was used in western blot on mouse samples (fig 4). EMBO J (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology TDP 43 antibody (Cell signaling, 3448) was used in western blot on mouse samples (fig 1). Sci Rep (2016) ncbi |
MilliporeSigma
domestic rabbit polyclonal |
| MilliporeSigma TDP 43 antibody (Sigma, T1580) was used in immunohistochemistry on mouse samples at 1:1000 (fig s5c) and in western blot on mouse samples at 1:5000 (fig 3a). Nature (2017) ncbi |
domestic rabbit polyclonal |
| In order to show that expression of human TDP-43 impairs small interfering RNA silencing, the major post-transcriptional mechanism of retrotransposable element control in somatic tissue, MilliporeSigma TDP 43 antibody (Sigma Aldrich, SAB4200223) was used in immunohistochemistry on human samples at 1:500 (fig s3b). PLoS Genet (2017) ncbi |
domestic rabbit polyclonal |
| MilliporeSigma TDP 43 antibody (Sigma, T1580) was used in immunohistochemistry - frozen section on human samples at 1:50 (fig 7), in western blot on human samples (fig 3) and in immunocytochemistry on mouse samples at 1:50 (fig 2). J Neurosci Res (2016) ncbi |
Articles Reviewed
- Latimer C, Burke B, Liachko N, Currey H, Kilgore M, Gibbons L, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathol Commun. 2019;7:9 pubmed publisher
- Hill S, Mordes D, Cameron L, Neuberg D, Landini S, Eggan K, et al. Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage. Proc Natl Acad Sci U S A. 2016;113:E7701-E7709 pubmed
- Matsukawa K, Hashimoto T, Matsumoto T, Ihara R, Chihara T, Miura M, et al. Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43. J Biol Chem. 2016;291:23464-23476 pubmed
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