Planta Medica

Thank You for 1000 Followers! We are thrilled to announce that we have reached the remarkable milestone of 1000 followers on our LinkedIn channel, and it's all because of you - our esteemed authors, readers and supporters! A massive thank you to the Society for Medicinal Plant and Natural Product Research (GA) and especially to Michael Heinrich, Robert Fürst, Oliver Kayser, Olaf Kelber and Antigoni Cheilari! Your continuous contributions and support have been crucial to our success. Thank you for being a part of our growing network. We are excited to keep building on this momentum and celebrating more achievements together. Let's grow together! #PlantaMedica #LetsGrowTogether 🌳

A new Special Issue of Planta Medica is out! Celebrating the Austrian Pharmacognosy and being dedicated to Rudolf Bauer Chlodwig Franz Brigitte Kopp and Hermann Stuppner Read here: https://lnkd.in/ehntUdun #PlantaMedica #LetsGrowTogether

A great FREE weekendread: Rationalising Optimal Dosing of Phytotherapeutics For Use In Children: Current Status – Potential Solutions – Actions Needed by Andreas Hensel et al. Read for FREE here: https://lnkd.in/daU6423r #PlantaMedica #LetsGrowTogether

Read for FREE: The Potential Pharmacological Effects of Natural Product Withaferin A in Cancer: Opportunities and Challenges for Clinical Translation By Geetanjali Devabattula et al. Read here for FREE: https://lnkd.in/eE3yhZ_S #PlantaMedica #LetsGrowTogether Fig. 2 A simplified diagram of the pharmacological effects of WA in cancer at the molecular level. WA induces cell cycle arrest at the G2/M phase by inhibiting the cyclinB1/CDck1 complex upon activation of p21 and Wee1 protein. Caspase mediated apoptosis by WA through PARP cleavage. WA generates ROS results in the activation of JNK and leads to mitochondrial dysfunction. The cells affected by ROS undergo apoptosis.WA inhibits angiogenesis by restricting the binding of the Sp-1 gene to its promoter region of the VEGF gene. Metastasis and tumor invasion are hindered by WA through suppression of EMT and vimentin expression and inhibition of metalloproteinases.

A great FREE Weekendread: Eye Diseases: When the Solution Comes from Plant Alkaloids by Riccardo Lorrai et al. Read for FREE here: https://lnkd.in/egXJrqJv #PlantaMedica #LetsGrowTogether Fig. 3 Summary of biotechnology approaches for plant alkaloid production based on microorganisms and plant cell culture. Potentially, all plant alkaloids can be produced by genetically engineered microorganisms, such as yeast and cell cultures. The advantage of using these approaches is that both microorganisms and plant cells can be grown in bioreactors that provide controlled growth conditions. In the figure, the different steps needed for the improvement of alkaloid production have been mentioned.

Check out the newest issue of Planta Medica! Read here: https://lnkd.in/eSkWqDdd #PlantaMedica #LetsGrowTogether

A great weekendread: Chemical Constituents from Agave applanata and Its Antihyperglycemic, Anti-inflammatory, and Antimicrobial Activities Associated with Its Tissue Repair Capability by A. Berenice Aguilar-Guadarrama et al. Read here: https://lnkd.in/e-pAprm9 #PlantaMedica #LetsGrowTogether Fig. 10 Representative images of wounds on days 0, 1, 3, 6, 8, 10, 13, and 15. a Effect of the hydroalcoholic extract (HAE). b Effect of saponin 2.

🎯 A new review article on the source of paclitaxel 🌿 📢 I am pleased to announce the publication of a new review article in Planta Medica, the official journal of the Society for Medicinal Plant and Natural Product Research (GA). This article examines the history of paclitaxel in cancer treatment. Despite its discovery over three decades ago, the primary metabolic precursor of paclitaxel continues to be sourced from European yew trees. Initial hopes for biotechnological production from fungi associated with yew trees did not come to fruition, leading to numerous publications reporting paclitaxel in various species — results that were not reproducible or scalable. This article examines the challenges faced in the commercial exploitation of paclitaxel, emphasizing the need for scientific skepticism and thorough peer review. It presents a case study on research ethics and the importance of avoiding questionable research practices in drug development. Read the full article to explore the lessons learned from the paclitaxel case and the importance of maintaining scientific rigor: https://lnkd.in/dSJQ48Yq #PharmaceuticalResearch #DrugDevelopment #ScientificIntegrity #PlantaMedica #Paclitaxel #CancerTreatment

🌿 Call for Submissions: Review Articles 🌿 Hello, I'm Robert Fürst, one of the Editors-in-Chief of Planta Medica, the official journal of the Society for Medicinal Plant and Natural Product Research (GA). 🔍 We are actively seeking insightful review articles from researchers and scholars in our field. 🔍 Our review articles enjoy high visibility and are freely available to the community, providing an exceptional opportunity for authors to contribute to the global dialogue on medicinal plants and natural product research. Whether you're summarizing recent advances or providing a new perspective on established knowledge, your work can play a crucial role in shaping future research directions. Submit your review articles to Planta Medica and take advantage of our wide-reaching platform to share your expertise and discoveries with the world: https://lnkd.in/dg598uTN For submission guidelines and more information, please visit our website: https://lnkd.in/ddMM5YGq Looking forward to your contributions! Robert Fürst Editor in Chief, Planta Medica #PlantaMedica #MedicinalPlants #NaturalProducts #AcademicPublishing #CallForPapers

A great FREE Weekendread: Research Progress of Natural Product Photosensitizers in Photodynamic Therapy by Xiaoxia Zhou et al. Read for Free here: https://lnkd.in/e4FVdjbX #PlantaMedica #LetsGrowTogether Fig. 1 Photodynamic therapy-related publications.