Extended Data Fig. 2: Enhanced CRISPR resistance evolution in ASM. | Nature

Extended Data Fig. 2: Enhanced CRISPR resistance evolution in ASM.

From: Bacterial biodiversity drives the evolution of CRISPR-based phage resistance

Extended Data Fig. 2

Proportion of P. aeruginosa that acquired surface modification or CRISPR-based immunity (or remained sensitive) 3 d.p.i. with phage DMS3vir when grown in ASM (6 replicates per treatment, with 24 colonies screened from each replicate, n = 30 biologically independent replicates). Deviance test: relationship between community composition and CRISPR; residual deviance (25, n = 30) = 1.26, P = 2.2 × 10−16; Tukey contrasts: monoculture versus mixed; z = −5.30, P = 1 × 10−4; monoculture versus A. baumannii; z = −5.60, P = 1 × 10−4; monoculture versus B. cenocepacia; z = −2.80, P = 0.02; monoculture versus S. aureus; z = −0.76, P = 0.93. Data are mean ± s.e.m

Source Data.

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