The discovery and characterization of regulatory RNAs have revolutionized our understanding of gene regulation. In this special issue, we present a series of review articles that delve into the complex world of regulatory RNAs.

This special issue provides comprehensive reviews of technological advances to investigate the 3D organization of the DNA in the nucleus and the functional implication of 4D Nucleome in physiology and human disease.

This special issue aims to provide comprehensive reviews of their activation mechanisms, functions, and potential as therapeutic targets for diverse immune disorders.

In this special issue, authors review several recent studies on the regulation of different types of cell death and their role in health and disease. They also discuss recent trends in cell death to improve our understanding of the role of different types of cell death pathways.