Nature Reviews Cancer publishes a dynamic and accessible mix of Reviews, Perspectives, Progress and Highlight articles on the most important primary research papers. All Reviews and Perspectives are carefully commissioned, written by leaders in the field and subject to rigorous peer-review – so that readers receive independent, high-quality and authoritative articles in each issue. The journal’s broad scope captures the essence of modern multidisciplinary cancer research – integrating cancer biology with new approaches to treatment, diagnosis and prevention. Non-specialists will benefit from the glossary and highlighted references, busy scientists will appreciate the ‘At-a-glance’ summaries, and experts will value the insight provided by top names in their field. Nature Reviews Cancer is the premier teaching and reference resource in cancer and has become the ‘must read’ review journal of cancer researchers worldwide. http://feeds.nature.com/nrc/rss/current Nature Publishing Group en © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Reviews Cancer © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com

https://www.nature.com/uploads/product/nrc/rss.gif http://feeds.nature.com/nrc/rss/current https://www.nature.com/articles/s41568-024-00722-6 Nature Reviews Cancer, Published online: 04 July 2024; doi:10.1038/s41568-024-00722-6In this study, Allan Balmain and colleagues used a mouse model to monitor stem cell networks at single-cell resolution during skin carcinogenesis, revealing two cancer stem cell states, rapid cycling and plasticity, between which cells can transition to drive tumour initiation, progression and therapy resistance.]]> Daniela Senft doi:10.1038/s41568-024-00722-6 Nature Reviews Cancer, Published online: 2024-07-04; | doi:10.1038/s41568-024-00722-6 2024-07-04 Nature Reviews Cancer 10.1038/s41568-024-00722-6 https://www.nature.com/articles/s41568-024-00722-6 https://www.nature.com/articles/s41568-024-00718-2 Nature Reviews Cancer, Published online: 02 July 2024; doi:10.1038/s41568-024-00718-2The practice of posting preprint manuscripts on servers such as bioRxiv has become increasingly common. In this Comment, Hindle and Sever explore the utility of preprints for advancing researchers careers.]]> Samantha HindleRichard Sever doi:10.1038/s41568-024-00718-2 Nature Reviews Cancer, Published online: 2024-07-02; | doi:10.1038/s41568-024-00718-2 2024-07-02 Nature Reviews Cancer 10.1038/s41568-024-00718-2 https://www.nature.com/articles/s41568-024-00718-2 https://www.nature.com/articles/s41568-024-00719-1 Nature Reviews Cancer, Published online: 01 July 2024; doi:10.1038/s41568-024-00719-1The ability of prenatal cell-free DNA sequencing to incidentally detect occult maternal malignancies was first documented over a decade ago, yet coordinated follow-up of pregnant people who receive these results is still lacking in many countries. Here we provide a call to action for oncologists to become more involved in diagnosing and managing these cases.]]> Amy E. TurriffDiana W. Bianchi doi:10.1038/s41568-024-00719-1 Nature Reviews Cancer, Published online: 2024-07-01; | doi:10.1038/s41568-024-00719-1 2024-07-01 Nature Reviews Cancer 10.1038/s41568-024-00719-1 https://www.nature.com/articles/s41568-024-00719-1 https://www.nature.com/articles/s41568-024-00717-3 Nature Reviews Cancer, Published online: 25 June 2024; doi:10.1038/s41568-024-00717-3Patient progression and response to immunotherapy are directly influenced by the presence and quality of tumour-infiltrating leukocytes (TILs). In a recent Cell publication, Wang, Zeng et al. demonstrate the functional role of circadian rhythms in altering TIL functionality and quantity, highlighting the therapeutic potential of leveraging this understanding.]]> Gabrielle Brewer doi:10.1038/s41568-024-00717-3 Nature Reviews Cancer, Published online: 2024-06-25; | doi:10.1038/s41568-024-00717-3 2024-06-25 Nature Reviews Cancer 10.1038/s41568-024-00717-3 https://www.nature.com/articles/s41568-024-00717-3 https://www.nature.com/articles/s41568-024-00720-8 Nature Reviews Cancer, Published online: 21 June 2024; doi:10.1038/s41568-024-00720-8This month, Nature Reviews Cancer launches Roadmap articles, in which we ask authors to provide a sense of direction to a field to encourage new lines of thinking and experimentation, as well as opportunities for collaboration.]]> doi:10.1038/s41568-024-00720-8 Nature Reviews Cancer, Published online: 2024-06-21; | doi:10.1038/s41568-024-00720-8 2024-06-21 Nature Reviews Cancer 10.1038/s41568-024-00720-8 https://www.nature.com/articles/s41568-024-00720-8 https://www.nature.com/articles/s41568-024-00708-4 Nature Reviews Cancer, Published online: 19 June 2024; doi:10.1038/s41568-024-00708-4In this Roadmap, Boire et al. consider the immediate causes of mortality in patients with cancer, a topic not often considered in either preclinical or clinical research, and provide recommendations for how we can stimulate research to advance our mechanistic understanding of these causes with a long-term view to improving the quality of life for patients with late-stage cancer.]]> Adrienne BoireKaty BurkeThomas R. CoxTheresa GuiseMariam Jamal-HanjaniTobias JanowitzRosandra KaplanRebecca LeeCharles SwantonMatthew G. Vander HeidenErik Sahai doi:10.1038/s41568-024-00708-4 Nature Reviews Cancer, Published online: 2024-06-19; | doi:10.1038/s41568-024-00708-4 2024-06-19 Nature Reviews Cancer 10.1038/s41568-024-00708-4 https://www.nature.com/articles/s41568-024-00708-4 https://www.nature.com/articles/s41568-024-00704-8 Nature Reviews Cancer, Published online: 17 June 2024; doi:10.1038/s41568-024-00704-8Although there has been increasing interest in developing models that mimic the tumour microenvironment (TME), these models often fail to replicate the complex 3D fibre architectures observed in tumours. Here, Ashworth and Cox address this, discuss the current design and fabrication challenges, and outline state-of-the-art biomaterial technologies useful for recreating tissue-specific 3D architectures in vitro.]]> J. C. AshworthT. R. Cox doi:10.1038/s41568-024-00704-8 Nature Reviews Cancer, Published online: 2024-06-17; | doi:10.1038/s41568-024-00704-8 2024-06-17 Nature Reviews Cancer 10.1038/s41568-024-00704-8 https://www.nature.com/articles/s41568-024-00704-8 https://www.nature.com/articles/s41568-024-00699-2 Nature Reviews Cancer, Published online: 17 June 2024; doi:10.1038/s41568-024-00699-2The tumour immune microenvironment greatly affects responses to immune checkpoint therapies. In this Perspective, Zemek et al. explore the dynamic changes in response to both immunotherapy and conventional treatment and advocate for strategic combination therapies over time to enhance antitumour immune responses.]]> Rachael M. ZemekValsamo AnagnostouInês Pires da SilvaGeorgina V. LongWillem Joost Lesterhuis doi:10.1038/s41568-024-00699-2 Nature Reviews Cancer, Published online: 2024-06-17; | doi:10.1038/s41568-024-00699-2 2024-06-17 Nature Reviews Cancer 10.1038/s41568-024-00699-2 https://www.nature.com/articles/s41568-024-00699-2 -