Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defence mechanisms, how the body defends itself against disease, and what happens when it all goes wrong. Nature Reviews Immunology provides in-depth coverage of this field, from fundamental mechanisms to translational aspects of basic research, and reviews the field’s most important developments. All Review and Perspective articles are carefully commissioned by the editors and written by leaders in the field. Articles are subject to rigorous peer review and provide high-quality and authoritative coverage of the field in each issue. Articles are carefully tailored by the editors to provide accessible information for non-specialists, and this is additionally enhanced with the use of Glossary terms and highlighted references. Each issue also contains Research Highlight articles – short pieces written by the editors that summarize the results from recent hot research papers. http://feeds.nature.com/nri/rss/current Nature Publishing Group en © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Reviews Immunology © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com

https://www.nature.com/uploads/product/nri/rss.gif http://feeds.nature.com/nri/rss/current https://www.nature.com/articles/s41577-024-01043-3 Nature Reviews Immunology, Published online: 24 June 2024; doi:10.1038/s41577-024-01043-3Here, the authors review the single-cell sequencing studies of rheumatic and allergic diseases, providing insight into disease pathogenesis, biomarkers and therapeutic targets.]]> Masayuki NishideHiroshi ShimagamiAtsushi Kumanogoh doi:10.1038/s41577-024-01043-3 Nature Reviews Immunology, Published online: 2024-06-24; | doi:10.1038/s41577-024-01043-3 2024-06-24 Nature Reviews Immunology 10.1038/s41577-024-01043-3 https://www.nature.com/articles/s41577-024-01043-3 https://www.nature.com/articles/s41577-024-01056-y Nature Reviews Immunology, Published online: 11 June 2024; doi:10.1038/s41577-024-01056-yAn adoptive cellular therapy based on γδ T cells, which were engineered to secrete a tumour-targeting opsonin as well as an IL-15 superagonist, controlled tumour growth in a mouse model of patient-derived osteosarcoma.]]> Alexandra Flemming doi:10.1038/s41577-024-01056-y Nature Reviews Immunology, Published online: 2024-06-11; | doi:10.1038/s41577-024-01056-y 2024-06-11 Nature Reviews Immunology 10.1038/s41577-024-01056-y https://www.nature.com/articles/s41577-024-01056-y https://www.nature.com/articles/s41577-024-01054-0 Nature Reviews Immunology, Published online: 11 June 2024; doi:10.1038/s41577-024-01054-0A study by Nakayama et al. shows that heart failure causes epigenetic changes in haematopoietic stem cells that predispose to further heart disease and comorbidity.]]> Alexandra Flemming doi:10.1038/s41577-024-01054-0 Nature Reviews Immunology, Published online: 2024-06-11; | doi:10.1038/s41577-024-01054-0 2024-06-11 Nature Reviews Immunology 10.1038/s41577-024-01054-0 https://www.nature.com/articles/s41577-024-01054-0 https://www.nature.com/articles/s41577-024-01041-5 Nature Reviews Immunology, Published online: 11 June 2024; doi:10.1038/s41577-024-01041-5Malaria remains a devastating human disease. Although malaria vaccines are available, their limited efficacy and protective duration are problematic. In this Review, the authors discuss how immunoregulatory networks that likely develop to prevent disease during malaria may also impede prevention and control measures.]]> Michelle J. BoyleChristian R. EngwerdaPrasanna Jagannathan doi:10.1038/s41577-024-01041-5 Nature Reviews Immunology, Published online: 2024-06-11; | doi:10.1038/s41577-024-01041-5 2024-06-11 Nature Reviews Immunology 10.1038/s41577-024-01041-5 https://www.nature.com/articles/s41577-024-01041-5 https://www.nature.com/articles/s41577-024-01055-z Nature Reviews Immunology, Published online: 10 June 2024; doi:10.1038/s41577-024-01055-zCAR T cell therapy alleviates type 2 airway inflammation in mouse models of asthma.]]> Yvonne Bordon doi:10.1038/s41577-024-01055-z Nature Reviews Immunology, Published online: 2024-06-10; | doi:10.1038/s41577-024-01055-z 2024-06-10 Nature Reviews Immunology 10.1038/s41577-024-01055-z https://www.nature.com/articles/s41577-024-01055-z https://www.nature.com/articles/s41577-024-01049-x Nature Reviews Immunology, Published online: 03 June 2024; doi:10.1038/s41577-024-01049-xThis Comment discusses the potential effects of ultra-processed foods (UPFs) on the immune system independently of obesity, by which UPFs might dysregulate the balance between the gut microbiota and immune cells.]]> Katherine A. MakiMichael N. SackKevin D. Hall doi:10.1038/s41577-024-01049-x Nature Reviews Immunology, Published online: 2024-06-03; | doi:10.1038/s41577-024-01049-x 2024-06-03 Nature Reviews Immunology 10.1038/s41577-024-01049-x https://www.nature.com/articles/s41577-024-01049-x https://www.nature.com/articles/s41577-024-01035-3 Nature Reviews Immunology, Published online: 03 June 2024; doi:10.1038/s41577-024-01035-3Recent clinical studies show that chimeric antigen receptor (CAR) T cells, best known for treating B cell malignancies, can be used to treat patients with various B cell-driven autoimmune diseases. Here, the authors update us with the progress so far and the considerations for further improving and extending their therapeutic application.]]> James B. ChungJennifer N. BrudnoDominic BorieJames N. Kochenderfer doi:10.1038/s41577-024-01035-3 Nature Reviews Immunology, Published online: 2024-06-03; | doi:10.1038/s41577-024-01035-3 2024-06-03 Nature Reviews Immunology 10.1038/s41577-024-01035-3 https://www.nature.com/articles/s41577-024-01035-3 https://www.nature.com/articles/s41577-024-01040-6 Nature Reviews Immunology, Published online: 03 June 2024; doi:10.1038/s41577-024-01040-6This Review provides a guide to the memory cells of the adaptive immune system, comprising memory T cells, memory B cells and plasma cells; it covers their formation, function, heterogeneity, localization, regulation and maintenance, and the crucial technological advances that allowed their discovery.]]> Nora LamYoonSeung LeeDonna L. Farber doi:10.1038/s41577-024-01040-6 Nature Reviews Immunology, Published online: 2024-06-03; | doi:10.1038/s41577-024-01040-6 2024-06-03 Nature Reviews Immunology 10.1038/s41577-024-01040-6 https://www.nature.com/articles/s41577-024-01040-6 -