3WCY,3SE4,2KZ1,3G9V,4DOH,1A21,3LQM


Conserved Protein Domain Family
Interfer-bind
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pfam09294: Interfer-bind (this model, PSSM-Id:286387 is obsolete and has been replaced by 462746)
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Interferon-alpha/beta receptor, fibronectin type III
Members of this family adopt a secondary structure consisting of seven beta-strands arranged in an immunoglobulin-like beta-sandwich, in a Greek-key topology. They are required for binding to interferon-alpha.
Links
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Statistics
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PSSM-Id: 286387
Aligned: 37 rows
Threshold Bit Score: 68.5253
Created: 13-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3WCY_A   100 AHMSPPEVRLEAEDKAILVHISPP--------G---QDGNMWALEKpSFSYTIRIWQKS--SS----D---KKTINSTYY 159 house mouse
O35664   132 APLEPPEFEIVGFTDHINVTMEFPpvts-kiiQ---EKMKTTPFVI-KEQIGDSVRKKH--EP----K---VNNVTGNFT 197 house mouse
2KZ1_B   105 MSFEPPEFEIVGFTNHINVMVKFPs--------------IVEEELQfDLSLVIEEQSEGivKKhkpeI---KGNMSGNFT 167 human
Q95141   132 KPLDPPEFEIVGFTNHISVNVKFQf-------D---SPGILSEELQfYLAFIEEHAGNS--VKrhqpQ---ITGNITKNF 196 cattle
A0FJH7   115 TIIGPPVIFLSGCGDCLNISISLPne-----sR---KDDKLRRFYN-SVSYSIS-WKKH--GNnevrE---ILRSQEPSK 179 zebrafish
4DOH_E   107 TQIGPPEVALTTDEKSISVVLTAPekwkrnpeD---LPVSMQQIYS-NLKYNVSVLNTK--SN----R---TWSQCVTNH 173 human
CAD67769 123 TIFGPPQMSVEVENSNAIVTVKGPmryqpnfqM---PAVSMATIYP-HMMYNLSIRNTY--RN----K---TSHFILSSG 189 spotted green puffe...
CAJ29460 130 TVLGAPLVDVTVRQNHIDITLKGPfrw---rmKrmkKEKSLWKIIP-NMIYKVSVFNSR--SN----R---TDVFRLTNG 196 zebrafish
AAD13677 128 TFLGPPEFNLSSCVHCINITIKLPpthl-rknG---KLLSLFDIYN-KVNYEITLRTVG--EEh---KrspEKVTEEPFS 197 chicken
CAD67763 108 TILGPPKVLLAGCDACLHVRVVLAggg---ggS----GKSLHGFY--KPTYILTIRNKA--EQ----R---TRRTPYKTS 169 spotted green puffe...

3WCY_A   160 VEKIPELLPETTYCLEVKAIHPSLKKHSNYSTVQCISTT 198 house mouse
O35664   198 F-VLRDLLPKTNYCVSLYF----DDDPAIKSPLKCIVLQ 231 house mouse
2KZ1_B   168 Y-IIDKLIPNTNYCVSVYL-EHSDEQAVIKSPLKCTLLP 204 human
Q95141   197 NYVIDKLIPNTNYCISVYF-EPKDPRKINRSPLKCTLFR 234 cattle
A0FJH7   180 QYVLENLQPGVQYCVKVLP-QINSNQNTQPSSWQCEYTS 217 zebrafish
4DOH_E   174 TLVLTWLEPNTLYCVHVESFVPGPPRRAQPSEKQCARTL 212 human
CAD67769 190 LYKHHLAEYNKEYCFSVKAKFLAMPVQCQSSEWQCITTP 228 spotted green pufferfish
CAJ29460 197 SLSLGELEFSTQFCVVAQAQSESIPLSYIPSQKQCVHTP 235 zebrafish
AAD13677 198 I-VIEELYPNRNYCVSVMVT-ASLNKHSIPSAWKCITTd 234 chicken
CAD67763 170 NFTVLHLHRNTEYCIRVNV-SIVLNQNTHPSGWTCAFTS 207 spotted green pufferfish
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