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    mltG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945660, updated on 24-Aug-2024

    Summary

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    Official Symbol
    mltG
    Primary source
    ASAP:ABE-0003712
    Locus tag
    b1097
    See related
    ECOCYC:EG11494
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1083; yceG
    Summary
    Overexpression causes abnormal biofilm architecture and increased crystal violet staining. [More information is available at EcoGene: EG11494]. yceG may be part of a 5-gene operon consisting of the pabC, yceG, tmk, holB, and ycfH genes . [More information is available at EcoCyc: EG11494].
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    Genomic context

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    Sequence:
    NC_000913.3 (1154112..1155134)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 3-oxoacyl-[acyl carrier protein] synthase 2 Neighboring gene aminodeoxychorismate lyase Neighboring gene Tmk Neighboring gene DNA polymerase III subunit delta' Neighboring gene putative metal-dependent hydrolase YcfH

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MltG activity antagonizes cell wall synthesis by both types of peptidoglycan polymerases in Escherichia coli. Bohrhunter JL, et al. Mol Microbiol, 2021 Jun. PMID 33278861, Free PMC Article
    2. A method for the construction of in frame substitutions in operons: deletion of the essential Escherichia coli holB gene coding for a subunit of the DNA polymerase III holoenzyme. Chaperon DN. J Microbiol Methods, 2006 Apr. PMID 16083981
    3. Characterization and sequence of Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme. Green JM, et al. J Bacteriol, 1992 Aug. PMID 1644759, Free PMC Article
    4. Systematic characterization of Escherichia coli genes/ORFs affecting biofilm formation. Tenorio E, et al. FEMS Microbiol Lett, 2003 Aug 8. PMID 12900028
    5. Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria. Yunck R, et al. Mol Microbiol, 2016 Feb. PMID 26507882, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lytic endotransglycosylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lytic endotransglycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peptidoglycan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within peptidoglycan metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in outer membrane-bounded periplasmic space ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endolytic murein transglycosylase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1154112..1155134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415615.1 endolytic murein transglycosylase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415615.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6L7CFH8
      Conserved Domains (1) summary
      PRK10270
      Location:1 → 340
      PRK10270; putative aminodeoxychorismate lyase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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