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Vascular disorder of penis

MedGen UID:
102349
•Concept ID:
C0156307
•
Disease or Syndrome
Synonyms: Penile vascular disorder; Penile Vascular Disorder; penile vascular disorder; Penis vascular disorder; vascular disorder of penis
SNOMED CT: Penile vascular disorder (198029003); Penis vascular disorder (198029003); Vascular disorder of penis (198029003)
 
Monarch Initiative: MONDO:0022293

Definition

A non-neoplastic or neoplastic disorder that affects the blood vessels of the penis. Representative examples include atherosclerosis, venous leak, and hemangioma. [from NCI]

Professional guidelines

PubMed

Ultrasound evaluation of varicoceles: guidelines and recommendations of the European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for detection, classification, and grading.
Freeman S, Bertolotto M, Richenberg J, Belfield J, Dogra V, Huang DY, Lotti F, Markiet K, Nikolic O, Ramanathan S, Ramchandani P, Rocher L, Secil M, Sidhu PS, Skrobisz K, Studniarek M, Tsili A, Tuncay Turgut A, Pavlica P, Derchi LE; members of the ESUR-SPIWG WG
Eur Radiol 2020 Jan;30(1):11-25. Epub 2019 Jul 22 doi: 10.1007/s00330-019-06280-y. PMID: 31332561
Diagnosis of vascular diseases. Ultrasound investigations--guidelines.
Antignani PL, Benedetti-Valentini F, Aluigi L, Baroncelli TA, Camporese G, Failla G, Martinelli O, Palasciano GC, Pulli R, Rispoli P, Amato A, Amitrano M, Dorigo W, Gossetti B, Irace L, Laurito A, Magnoni F, Minucci S, Pedrini L, Righi D, Verlato F; Italian Society for Vascular Investigation
Int Angiol 2012 Oct;31(5 Suppl 1):1-77. PMID: 23470846
Type 5 phosphodiesterase inhibitors in the treatment of erectile dysfunction and cardiovascular disease.
Ravipati G, McClung JA, Aronow WS, Peterson SJ, Frishman WH
Cardiol Rev 2007 Mar-Apr;15(2):76-86. doi: 10.1097/01.crd.0000233904.77128.49. PMID: 17303994

Recent clinical studies

Etiology

Ultrasound evaluation of varicoceles: guidelines and recommendations of the European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for detection, classification, and grading.
Freeman S, Bertolotto M, Richenberg J, Belfield J, Dogra V, Huang DY, Lotti F, Markiet K, Nikolic O, Ramanathan S, Ramchandani P, Rocher L, Secil M, Sidhu PS, Skrobisz K, Studniarek M, Tsili A, Tuncay Turgut A, Pavlica P, Derchi LE; members of the ESUR-SPIWG WG
Eur Radiol 2020 Jan;30(1):11-25. Epub 2019 Jul 22 doi: 10.1007/s00330-019-06280-y. PMID: 31332561
Erectile dysfunction.
Yafi FA, Jenkins L, Albersen M, Corona G, Isidori AM, Goldfarb S, Maggi M, Nelson CJ, Parish S, Salonia A, Tan R, Mulhall JP, Hellstrom WJ
Nat Rev Dis Primers 2016 Feb 4;2:16003. doi: 10.1038/nrdp.2016.3. PMID: 27188339Free PMC Article
Erectile dysfunction.
McMahon CG
Intern Med J 2014 Jan;44(1):18-26. doi: 10.1111/imj.12325. PMID: 24450519
The penile tourniquet.
Parsons BA, Kalejaiye O, Mohammed M, Persad RA
Asian J Androl 2013 May;15(3):364-7. Epub 2013 Apr 1 doi: 10.1038/aja.2012.164. PMID: 23542140Free PMC Article
Micropenis.
Wiygul J, Palmer LS
ScientificWorldJournal 2011 Jul 28;11:1462-9. doi: 10.1100/tsw.2011.135. PMID: 21805015Free PMC Article

Diagnosis

US of the Penis: Beyond Erectile Dysfunction.
Kho YY, Lee SHE, Chin K, Sidek NZ, Ma VC, Seng DH, Cai S, Tan LW, Teo SM, Gogna A, Patel A, Venkatanarasimha N
Radiographics 2024 Jun;44(6):e230157. doi: 10.1148/rg.230157. PMID: 38814798
Ultrasound evaluation of varicoceles: guidelines and recommendations of the European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for detection, classification, and grading.
Freeman S, Bertolotto M, Richenberg J, Belfield J, Dogra V, Huang DY, Lotti F, Markiet K, Nikolic O, Ramanathan S, Ramchandani P, Rocher L, Secil M, Sidhu PS, Skrobisz K, Studniarek M, Tsili A, Tuncay Turgut A, Pavlica P, Derchi LE; members of the ESUR-SPIWG WG
Eur Radiol 2020 Jan;30(1):11-25. Epub 2019 Jul 22 doi: 10.1007/s00330-019-06280-y. PMID: 31332561
Penile imaging.
Shenoy-Bhangle A, Perez-Johnston R, Singh A
Radiol Clin North Am 2012 Nov;50(6):1167-81. doi: 10.1016/j.rcl.2012.08.009. PMID: 23122044
Micropenis.
Wiygul J, Palmer LS
ScientificWorldJournal 2011 Jul 28;11:1462-9. doi: 10.1100/tsw.2011.135. PMID: 21805015Free PMC Article
Superficial thrombophlebitis.
Luis Rodríguez-Peralto J, Carrillo R, Rosales B, Rodríguez-Gil Y
Semin Cutan Med Surg 2007 Jun;26(2):71-6. doi: 10.1016/j.sder.2007.02.002. PMID: 17544957

Therapy

Post Circumcision Corona Obliteration.
Naimer SA, Sivan B
J Pediatr Urol 2020 Jun;16(3):389.e1-389.e5. Epub 2020 Apr 21 doi: 10.1016/j.jpurol.2020.04.017. PMID: 32417116
Erectile dysfunction.
Yafi FA, Jenkins L, Albersen M, Corona G, Isidori AM, Goldfarb S, Maggi M, Nelson CJ, Parish S, Salonia A, Tan R, Mulhall JP, Hellstrom WJ
Nat Rev Dis Primers 2016 Feb 4;2:16003. doi: 10.1038/nrdp.2016.3. PMID: 27188339Free PMC Article
Erectile dysfunction.
McMahon CG
Intern Med J 2014 Jan;44(1):18-26. doi: 10.1111/imj.12325. PMID: 24450519
The penile tourniquet.
Parsons BA, Kalejaiye O, Mohammed M, Persad RA
Asian J Androl 2013 May;15(3):364-7. Epub 2013 Apr 1 doi: 10.1038/aja.2012.164. PMID: 23542140Free PMC Article
Micropenis.
Wiygul J, Palmer LS
ScientificWorldJournal 2011 Jul 28;11:1462-9. doi: 10.1100/tsw.2011.135. PMID: 21805015Free PMC Article

Prognosis

Maternal and neonatal trauma following operative vaginal delivery.
Muraca GM, Boutin A, Razaz N, Lisonkova S, John S, Ting JY, Scott H, Kramer MS, Joseph KS
CMAJ 2022 Jan 10;194(1):E1-E12. doi: 10.1503/cmaj.210841. PMID: 35012946Free PMC Article
Erectile dysfunction links to cardiovascular disease-defining the clinical value.
Orimoloye OA, Feldman DI, Blaha MJ
Trends Cardiovasc Med 2019 Nov;29(8):458-465. Epub 2019 Jan 11 doi: 10.1016/j.tcm.2019.01.002. PMID: 30665816
Erectile dysfunction - overview from a cardiovascular perspective.
Baumann F, Hehli D, Makaloski V, Schumacher M, Schönhofen H, Diehm N
Vasa 2017 Aug;46(5):347-353. Epub 2017 May 10 doi: 10.1024/0301-1526/a000627. PMID: 28486869
Mondor's disease: what's new since 1939?
Laroche JP, Galanaud J, Labau D, Van Kien AK, Brisot D, Boge G, Quéré I
Thromb Res 2012 Oct;130 Suppl 1:S56-8. doi: 10.1016/j.thromres.2012.08.276. PMID: 23026664
Cardiac uses of phosphodiesterase-5 inhibitors.
Schwartz BG, Levine LA, Comstock G, Stecher VJ, Kloner RA
J Am Coll Cardiol 2012 Jan 3;59(1):9-15. doi: 10.1016/j.jacc.2011.07.051. PMID: 22192662

Clinical prediction guides

Assessment of clinical conditions associated with Mondor disease.
Ito H, Ogawa Y, Shimojo N, Kawano S
Breast Dis 2022;41(1):273-278. doi: 10.3233/BD-210056. PMID: 35634842
Noninfectious Penile Lesions.
Teichman JMH, Mannas M, Elston DM
Am Fam Physician 2018 Jan 15;97(2):102-110. PMID: 29365226
Erectile dysfunction - overview from a cardiovascular perspective.
Baumann F, Hehli D, Makaloski V, Schumacher M, Schönhofen H, Diehm N
Vasa 2017 Aug;46(5):347-353. Epub 2017 May 10 doi: 10.1024/0301-1526/a000627. PMID: 28486869
Protein markers of malignant potential in penile and vulvar lichen sclerosus.
Carlson BC, Hofer MD, Ballek N, Yang XJ, Meeks JJ, Gonzalez CM
J Urol 2013 Aug;190(2):399-406. Epub 2013 Feb 8 doi: 10.1016/j.juro.2013.01.102. PMID: 23399649
Mondor's disease: what's new since 1939?
Laroche JP, Galanaud J, Labau D, Van Kien AK, Brisot D, Boge G, Quéré I
Thromb Res 2012 Oct;130 Suppl 1:S56-8. doi: 10.1016/j.thromres.2012.08.276. PMID: 23026664

Recent systematic reviews

What We Know About Penile Mondor's Disease.
Özkan B, Coşkuner ER
Sex Med Rev 2022 Jul;10(3):403-408. Epub 2022 Mar 3 doi: 10.1016/j.sxmr.2021.12.006. PMID: 35249861
Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations.
Bertolotto M, Freeman S, Richenberg J, Belfield J, Dogra V, Huang DY, Lotti F, Markiet K, Nikolic O, Ramanathan S, Ramchandani P, Rocher L, Secil M, Sidhu PS, Skrobisz K, Studniarek M, Tsili A, Turgut AT, Pavlica P, Derchi LE; Members of the ESUR-SPIWG WG
J Ultrasound 2020 Dec;23(4):487-507. Epub 2020 Jul 27 doi: 10.1007/s40477-020-00509-z. PMID: 32720266Free PMC Article
Epidemiology regarding penile prosthetic surgery.
Saavedra-Belaunde JA, Clavell-Hernandez J, Wang R
Asian J Androl 2020 Jan-Feb;22(1):2-7. doi: 10.4103/aja.aja_124_19. PMID: 31793443Free PMC Article
Endovascular Therapy for Vasculogenic Erectile Dysfunction: A Systematic Review and Meta-Analysis of Arterial and Venous Therapies.
Doppalapudi SK, Wajswol E, Shukla PA, Kolber MK, Singh MK, Kumar A, Fischman A, Rastinehad AR
J Vasc Interv Radiol 2019 Aug;30(8):1251-1258.e2. Epub 2019 May 17 doi: 10.1016/j.jvir.2019.01.024. PMID: 31104902
The endothelial-erectile dysfunction connection: an essential update.
Costa C, Virag R
J Sex Med 2009 Sep;6(9):2390-404. Epub 2009 Jun 11 doi: 10.1111/j.1743-6109.2009.01356.x. PMID: 19523038

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