U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Stasis ulcer

MedGen UID:
12048
•Concept ID:
C0042344
•
Disease or Syndrome
Synonyms: Hypertension Ulcer, Venous; Hypertension Ulcers, Venous; Stasis Ulcer; Stasis Ulcer, Venous; Stasis Ulcers; Stasis Ulcers, Venous; Ulcer, Stasis; Ulcer, Varicose; Ulcer, Venous; Ulcer, Venous Hypertension; Ulcer, Venous Stasis; Ulcers, Stasis; Ulcers, Varicose; Ulcers, Venous; Ulcers, Venous Hypertension; Ulcers, Venous Stasis; Varicose Ulcer; Varicose Ulcers; Venous Hypertension Ulcer; Venous Hypertension Ulcers; Venous Stasis Ulcer; Venous Stasis Ulcers; Venous Ulcer; Venous Ulcers
SNOMED CT: Stasis leg ulcer (41915009); Gravitational ulcer (41915009); Stasis ulcer (41915009); Venous ulcer (41915009); Varicose ulcer (41915009)

Definition

Skin breakdown or ulceration in the drainage area of a VARICOSE VEIN, usually in the leg. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStasis ulcer

Professional guidelines

PubMed

Prevention and treatment of the post-thrombotic syndrome and of the chronic thromboembolic pulmonary hypertension.
Pesavento R, Prandoni P
Expert Rev Cardiovasc Ther 2015 Feb;13(2):193-207. Epub 2015 Jan 12 doi: 10.1586/14779072.2015.1000306. PMID: 25577951
Diagnosis and treatment of venous ulcers.
Collins L, Seraj S
Am Fam Physician 2010 Apr 15;81(8):989-96. PMID: 20387775
Optimal treatment of venous (stasis) ulcers in elderly patients.
Hansson C
Drugs Aging 1994 Nov;5(5):323-34. doi: 10.2165/00002512-199405050-00002. PMID: 7833586

Recent clinical studies

Etiology

Stasis ulcer and hydronephrosis after severe genital prolapse: a case report.
Leanza V, Di Stefano A, Paladino EC, Rivoli L, Distefano REC, Palumbo M
J Med Case Rep 2022 Apr 28;16(1):173. doi: 10.1186/s13256-022-03405-8. PMID: 35477487Free PMC Article
Nutrition and Chronic Wounds: Improving Clinical Outcomes.
Molnar JA, Vlad LG, Gumus T
Plast Reconstr Surg 2016 Sep;138(3 Suppl):71S-81S. doi: 10.1097/PRS.0000000000002676. PMID: 27556777
Endovenous laser ablation of great saphenous vein and perforator veins improves venous stasis ulcer healing.
Abdul-Haqq R, Almaroof B, Chen BL, Panneton JM, Parent FN
Ann Vasc Surg 2013 Oct;27(7):932-9. Epub 2013 May 24 doi: 10.1016/j.avsg.2012.09.014. PMID: 23711972
Diagnosis and treatment of venous ulcers.
Collins L, Seraj S
Am Fam Physician 2010 Apr 15;81(8):989-96. PMID: 20387775
Patients with venous stasis ulceration have increased monocyte-platelet aggregation.
Peyton BD, Rohrer MJ, Furman MI, Barnard MR, Rodino LJ, Benoit SE, Hechtman HB, Valeri CR, Michelson AD
J Vasc Surg 1998 Jun;27(6):1109-15; discussion 1115-6. doi: 10.1016/s0741-5214(98)70013-8. PMID: 9652473

Diagnosis

Chronic, nonhealing leg ulcer.
Crasto D, Cruse A, Byrd A, Brodell R
J Fam Pract 2020 Oct;69(8):417;418;420. PMID: 33175924
Nutrition and Chronic Wounds: Improving Clinical Outcomes.
Molnar JA, Vlad LG, Gumus T
Plast Reconstr Surg 2016 Sep;138(3 Suppl):71S-81S. doi: 10.1097/PRS.0000000000002676. PMID: 27556777
Prevention and treatment of the post-thrombotic syndrome and of the chronic thromboembolic pulmonary hypertension.
Pesavento R, Prandoni P
Expert Rev Cardiovasc Ther 2015 Feb;13(2):193-207. Epub 2015 Jan 12 doi: 10.1586/14779072.2015.1000306. PMID: 25577951
Diagnosis and treatment of venous ulcers.
Collins L, Seraj S
Am Fam Physician 2010 Apr 15;81(8):989-96. PMID: 20387775
The lanolin paradox.
Wolf R
Dermatology 1996;192(3):198-202. doi: 10.1159/000246365. PMID: 8726630

Therapy

Resolving Epibole With Polymeric Membrane Dressings in Home Care.
Bare KS, Drain J
J Wound Ostomy Continence Nurs 2017 Jan/Feb;44(1):89-92. doi: 10.1097/WON.0000000000000296. PMID: 28060006
Prevention and treatment of the post-thrombotic syndrome and of the chronic thromboembolic pulmonary hypertension.
Pesavento R, Prandoni P
Expert Rev Cardiovasc Ther 2015 Feb;13(2):193-207. Epub 2015 Jan 12 doi: 10.1586/14779072.2015.1000306. PMID: 25577951
Endovenous laser ablation of great saphenous vein and perforator veins improves venous stasis ulcer healing.
Abdul-Haqq R, Almaroof B, Chen BL, Panneton JM, Parent FN
Ann Vasc Surg 2013 Oct;27(7):932-9. Epub 2013 May 24 doi: 10.1016/j.avsg.2012.09.014. PMID: 23711972
Hyperhomocysteinemia in patients with stasis dermatitis and ulcer: a novel finding with important therapeutic implications.
Durmazlar SP, Akgul A, Eskioglu F
J Dermatolog Treat 2009;20(6):336-9. doi: 10.3109/09546630902775069. PMID: 19954389
The lanolin paradox.
Wolf R
Dermatology 1996;192(3):198-202. doi: 10.1159/000246365. PMID: 8726630

Prognosis

Massive esophageal bleeding in long-standing achalasia complicated by esophageal carcinoma and aspirin-induced stasis ulcer: Case report.
Cho JH
Medicine (Baltimore) 2019 Jul;98(30):e16519. doi: 10.1097/MD.0000000000016519. PMID: 31348265Free PMC Article
Improving diabetic patient transition to home healthcare: leading risk factors for 30-day readmission.
Chen HF, Popoola T, Radhakrishnan K, Suzuki S, Homan S
Am J Manag Care 2015 Jun;21(6):440-50. PMID: 26168064
Diagnosis and treatment of venous ulcers.
Collins L, Seraj S
Am Fam Physician 2010 Apr 15;81(8):989-96. PMID: 20387775
Altered proliferative responses of dermal fibroblasts to TGF-beta1 may contribute to chronic venous stasis ulcer.
Lal BK, Saito S, Pappas PJ, Padberg FT Jr, Cerveira JJ, Hobson RW 2nd, Durán WN
J Vasc Surg 2003 Jun;37(6):1285-93. doi: 10.1016/s0741-5214(02)75295-6. PMID: 12764277
Effect of the National Resident Assessment Instrument on selected health conditions and problems.
Fries BE, Hawes C, Morris JN, Phillips CD, Mor V, Park PS
J Am Geriatr Soc 1997 Aug;45(8):994-1001. doi: 10.1111/j.1532-5415.1997.tb02972.x. PMID: 9256854

Clinical prediction guides

Relationship Between pH Shifts and Rate of Healing in Chronic Nonhealing Venous Stasis Lower-Extremity Wounds.
Tarricone A, De La Mata K, Chen S, Krishnan P, Landau S, Soave R
J Foot Ankle Surg 2020 Jul-Aug;59(4):748-752. Epub 2020 Mar 6 doi: 10.1053/j.jfas.2020.01.007. PMID: 32151549
Massive esophageal bleeding in long-standing achalasia complicated by esophageal carcinoma and aspirin-induced stasis ulcer: Case report.
Cho JH
Medicine (Baltimore) 2019 Jul;98(30):e16519. doi: 10.1097/MD.0000000000016519. PMID: 31348265Free PMC Article
Treatment of refractory venous stasis ulcers with autologous platelet-rich plasma and light-emitting diodes: a pilot study.
Park KY, Kim IS, Yeo IK, Kim BJ, Kim MN
J Dermatolog Treat 2013 Oct;24(5):332-5. Epub 2013 Jun 27 doi: 10.3109/09546634.2012.735637. PMID: 23738854
Endovenous laser ablation of great saphenous vein and perforator veins improves venous stasis ulcer healing.
Abdul-Haqq R, Almaroof B, Chen BL, Panneton JM, Parent FN
Ann Vasc Surg 2013 Oct;27(7):932-9. Epub 2013 May 24 doi: 10.1016/j.avsg.2012.09.014. PMID: 23711972
High prevalence of nonthrombotic iliac vein lesions in chronic venous disease: a permissive role in pathogenicity.
Raju S, Neglen P
J Vasc Surg 2006 Jul;44(1):136-43; discussion 144. doi: 10.1016/j.jvs.2006.02.065. PMID: 16828437

Recent systematic reviews

Active debridement of venous leg ulcers: a literature review to inform clinical practice.
Hall L, Adderley U
Br J Community Nurs 2019 Jun 1;24(Sup6):S24-S29. doi: 10.12968/bjcn.2019.24.Sup6.S24. PMID: 31166789
Heterogeneity of wound outcome measures in RCTs of treatments for VLUs: a systematic review.
Gethin G, Killeen F, Devane D
J Wound Care 2015 May;24(5):211-2, 214, 216 passim. doi: 10.12968/jowc.2015.24.5.211. PMID: 25970758

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...
    -