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Prehypertension

MedGen UID:
352152
Concept ID:
C1696708
Disease or Syndrome
Synonyms: Pre Hypertension; Pre-Hypertension; Pre-Hypertensions; Prehypertensions
SNOMED CT: Prehypertension (702817009)

Definition

Average of two or more properly measured readings at each of two or more visits after an initial screen with a systolic 120 to 139 mmHg or diastolic 80 to 89 mmHg. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrehypertension

Professional guidelines

PubMed

Wang YJ, Li ZX, Gu HQ, Zhai Y, Zhou Q, Jiang Y, Zhao XQ, Wang YL, Yang X, Wang CJ, Meng X, Li H, Liu LP, Jing J, Wu J, Xu AD, Dong Q, Wang D, Wang WZ, Ma XD, Zhao JZ; China Stroke Statistics Writing Committee
Stroke Vasc Neurol 2022 Oct;7(5):415-450. Epub 2022 Apr 20 doi: 10.1136/svn-2021-001374. PMID: 35443985Free PMC Article
Mahmood S, Shah KU, Khan TM, Nawaz S, Rashid H, Baqar SWA, Kamran S
Ir J Med Sci 2019 May;188(2):437-452. Epub 2018 Aug 22 doi: 10.1007/s11845-018-1889-8. PMID: 30136222
Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM; SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN
Pediatrics 2017 Sep;140(3) Epub 2017 Aug 21 doi: 10.1542/peds.2017-1904. PMID: 28827377

Recent clinical studies

Etiology

Li X, Chang P, Wu M, Jiang Y, Gao Y, Chen H, Tao L, Wei D, Yang X, Xiong X, Yang Y, Pan X, Zhao R, Yang F, Sun J, Yang S, Tian L, He X, Wang E, Yang Y, Xing Y
JAMA Netw Open 2024 Feb 5;7(2):e2354937. doi: 10.1001/jamanetworkopen.2023.54937. PMID: 38335001Free PMC Article
Middeldorp ME, Ariyaratnam JP, Kamsani SH, Albert CM, Sanders P
J Hypertens 2022 Dec 1;40(12):2337-2352. Epub 2022 Oct 4 doi: 10.1097/HJH.0000000000003278. PMID: 36204994
Pescatello LS, Buchner DM, Jakicic JM, Powell KE, Kraus WE, Bloodgood B, Campbell WW, Dietz S, Dipietro L, George SM, Macko RF, McTiernan A, Pate RR, Piercy KL; 2018 PHYSICAL ACTIVITY GUIDELINES ADVISORY COMMITTEE*
Med Sci Sports Exerc 2019 Jun;51(6):1314-1323. doi: 10.1249/MSS.0000000000001943. PMID: 31095088
Kawabata Y, Ekuni D, Miyai H, Kataoka K, Yamane M, Mizutani S, Irie K, Azuma T, Tomofuji T, Iwasaki Y, Morita M
Am J Hypertens 2016 Mar;29(3):388-96. Epub 2015 Jul 23 doi: 10.1093/ajh/hpv117. PMID: 26208668
Nandeesha H, Bobby Z, Selvaraj N, Rajappa M
Clin Chim Acta 2015 Dec 7;451(Pt B):338-42. Epub 2015 Oct 23 doi: 10.1016/j.cca.2015.10.022. PMID: 26525963

Diagnosis

Fu J, Liu Y, Zhang L, Zhou L, Li D, Quan H, Zhu L, Hu F, Li X, Meng S, Yan R, Zhao S, Onwuka JU, Yang B, Sun D, Zhao Y
J Am Heart Assoc 2020 Oct 20;9(19):e016804. Epub 2020 Sep 25 doi: 10.1161/JAHA.120.016804. PMID: 32975166Free PMC Article
Byrd JB, Brook RD
Ann Intern Med 2019 May 7;170(9):ITC65-ITC80. doi: 10.7326/AITC201905070. PMID: 31060074
Wang Z, Chen Z, Zhang L, Wang X, Hao G, Zhang Z, Shao L, Tian Y, Dong Y, Zheng C, Wang J, Zhu M, Weintraub WS, Gao R; China Hypertension Survey Investigators
Circulation 2018 May 29;137(22):2344-2356. Epub 2018 Feb 15 doi: 10.1161/CIRCULATIONAHA.117.032380. PMID: 29449338
Cornelissen VA, Smart NA
J Am Heart Assoc 2013 Feb 1;2(1):e004473. doi: 10.1161/JAHA.112.004473. PMID: 23525435Free PMC Article
Elliott WJ
Curr Probl Cardiol 2007 Apr;32(4):201-59. doi: 10.1016/j.cpcardiol.2007.01.002. PMID: 17398315

Therapy

Fu J, Liu Y, Zhang L, Zhou L, Li D, Quan H, Zhu L, Hu F, Li X, Meng S, Yan R, Zhao S, Onwuka JU, Yang B, Sun D, Zhao Y
J Am Heart Assoc 2020 Oct 20;9(19):e016804. Epub 2020 Sep 25 doi: 10.1161/JAHA.120.016804. PMID: 32975166Free PMC Article
Pedralli ML, Marschner RA, Kollet DP, Neto SG, Eibel B, Tanaka H, Lehnen AM
Sci Rep 2020 May 6;10(1):7628. doi: 10.1038/s41598-020-64365-x. PMID: 32376984Free PMC Article
Wang Z, Chen Z, Zhang L, Wang X, Hao G, Zhang Z, Shao L, Tian Y, Dong Y, Zheng C, Wang J, Zhu M, Weintraub WS, Gao R; China Hypertension Survey Investigators
Circulation 2018 May 29;137(22):2344-2356. Epub 2018 Feb 15 doi: 10.1161/CIRCULATIONAHA.117.032380. PMID: 29449338
Cornelissen VA, Smart NA
J Am Heart Assoc 2013 Feb 1;2(1):e004473. doi: 10.1161/JAHA.112.004473. PMID: 23525435Free PMC Article
Elliott WJ
Curr Probl Cardiol 2007 Apr;32(4):201-59. doi: 10.1016/j.cpcardiol.2007.01.002. PMID: 17398315

Prognosis

Dimitrijev I, Radovanovic S, Vesic Z, Colakovic G, Selakovic V, Lackovic A, Djordjevic SS, Pesic M, Nesovic D, Lazarevic R, Djordjevic O, Mihaljevic O, Obradovic A, Vukicevic V, Janicijevic N, Radovanovic J
Medicina (Kaunas) 2024 May 16;60(5) doi: 10.3390/medicina60050824. PMID: 38793007Free PMC Article
Wang YJ, Li ZX, Gu HQ, Zhai Y, Zhou Q, Jiang Y, Zhao XQ, Wang YL, Yang X, Wang CJ, Meng X, Li H, Liu LP, Jing J, Wu J, Xu AD, Dong Q, Wang D, Wang WZ, Ma XD, Zhao JZ; China Stroke Statistics Writing Committee
Stroke Vasc Neurol 2022 Oct;7(5):415-450. Epub 2022 Apr 20 doi: 10.1136/svn-2021-001374. PMID: 35443985Free PMC Article
Egan BM, Stevens-Fabry S
Nat Rev Cardiol 2015 May;12(5):289-300. Epub 2015 Feb 17 doi: 10.1038/nrcardio.2015.17. PMID: 25687779
Huang Y, Su L, Cai X, Mai W, Wang S, Hu Y, Wu Y, Tang H, Xu D
Am Heart J 2014 Feb;167(2):160-168.e1. Epub 2013 Nov 6 doi: 10.1016/j.ahj.2013.10.023. PMID: 24439976
Brady TM
Pediatr Rev 2012 Dec;33(12):541-52. doi: 10.1542/pir.33-12-541. PMID: 23204396

Clinical prediction guides

Henkin JS, Pinto RS, Machado CLF, Wilhelm EN
Exp Gerontol 2023 Jun 15;177:112193. Epub 2023 May 16 doi: 10.1016/j.exger.2023.112193. PMID: 37121334
Kanegae H, Oikawa T, Kario K
Curr Hypertens Rep 2017 Oct 18;19(11):91. doi: 10.1007/s11906-017-0789-z. PMID: 29046988
Li J, Zhao F, Wang Y, Chen J, Tao J, Tian G, Wu S, Liu W, Cui Q, Geng B, Zhang W, Weldon R, Auguste K, Yang L, Liu X, Chen L, Yang X, Zhu B, Cai J
Microbiome 2017 Feb 1;5(1):14. doi: 10.1186/s40168-016-0222-x. PMID: 28143587Free PMC Article
Kawabata Y, Ekuni D, Miyai H, Kataoka K, Yamane M, Mizutani S, Irie K, Azuma T, Tomofuji T, Iwasaki Y, Morita M
Am J Hypertens 2016 Mar;29(3):388-96. Epub 2015 Jul 23 doi: 10.1093/ajh/hpv117. PMID: 26208668
Cornelissen VA, Smart NA
J Am Heart Assoc 2013 Feb 1;2(1):e004473. doi: 10.1161/JAHA.112.004473. PMID: 23525435Free PMC Article

Recent systematic reviews

Henkin JS, Pinto RS, Machado CLF, Wilhelm EN
Exp Gerontol 2023 Jun 15;177:112193. Epub 2023 May 16 doi: 10.1016/j.exger.2023.112193. PMID: 37121334
Fu J, Liu Y, Zhang L, Zhou L, Li D, Quan H, Zhu L, Hu F, Li X, Meng S, Yan R, Zhao S, Onwuka JU, Yang B, Sun D, Zhao Y
J Am Heart Assoc 2020 Oct 20;9(19):e016804. Epub 2020 Sep 25 doi: 10.1161/JAHA.120.016804. PMID: 32975166Free PMC Article
Song P, Zhang Y, Yu J, Zha M, Zhu Y, Rahimi K, Rudan I
JAMA Pediatr 2019 Dec 1;173(12):1154-1163. doi: 10.1001/jamapediatrics.2019.3310. PMID: 31589252Free PMC Article
Pescatello LS, Buchner DM, Jakicic JM, Powell KE, Kraus WE, Bloodgood B, Campbell WW, Dietz S, Dipietro L, George SM, Macko RF, McTiernan A, Pate RR, Piercy KL; 2018 PHYSICAL ACTIVITY GUIDELINES ADVISORY COMMITTEE*
Med Sci Sports Exerc 2019 Jun;51(6):1314-1323. doi: 10.1249/MSS.0000000000001943. PMID: 31095088
Cornelissen VA, Smart NA
J Am Heart Assoc 2013 Feb 1;2(1):e004473. doi: 10.1161/JAHA.112.004473. PMID: 23525435Free PMC Article

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