U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Chronic colitis

MedGen UID:
451030
•Concept ID:
C0267375
•
Disease or Syndrome
SNOMED CT: Chronic colitis (54597004)
 
HPO: HP:0100281

Definition

A chronic inflammatory disease of the large intestine (colon, cecum and rectum). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Chronic colitis

Professional guidelines

PubMed

Inflammatory Bowel Disease-Unclassified in Children: Diagnosis and Pharmacological Management.
D'Arcangelo G, Aloi M
Paediatr Drugs 2017 Apr;19(2):113-120. doi: 10.1007/s40272-017-0213-9. PMID: 28150131
Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer.
Zhang M, Viennois E, Prasad M, Zhang Y, Wang L, Zhang Z, Han MK, Xiao B, Xu C, Srinivasan S, Merlin D
Biomaterials 2016 Sep;101:321-40. Epub 2016 Jun 9 doi: 10.1016/j.biomaterials.2016.06.018. PMID: 27318094Free PMC Article
Ulcerative colitis: epidemiology, diagnosis, and management.
Feuerstein JD, Cheifetz AS
Mayo Clin Proc 2014 Nov;89(11):1553-63. Epub 2014 Sep 8 doi: 10.1016/j.mayocp.2014.07.002. PMID: 25199861

Recent clinical studies

Etiology

Wumei Wan attenuates angiogenesis and inflammation by modulating RAGE signaling pathway in IBD: Network pharmacology analysis and experimental evidence.
Duan ZL, Wang YJ, Lu ZH, Tian L, Xia ZQ, Wang KL, Chen T, Wang R, Feng ZY, Shi GP, Xu XT, Bu F, Ding Y, Jiang F, Zhou JY, Wang Q, Chen YG
Phytomedicine 2023 Mar;111:154658. Epub 2023 Jan 12 doi: 10.1016/j.phymed.2023.154658. PMID: 36706698
BAFF Blockade Attenuates DSS-Induced Chronic Colitis via Inhibiting NLRP3 Inflammasome and NF-κB Activation.
Zhang Y, Tao M, Chen C, Zhao X, Feng Q, Chen G, Fu Y
Front Immunol 2022;13:783254. Epub 2022 Mar 7 doi: 10.3389/fimmu.2022.783254. PMID: 35320937Free PMC Article
B. adolescentis ameliorates chronic colitis by regulating Treg/Th2 response and gut microbiota remodeling.
Fan L, Qi Y, Qu S, Chen X, Li A, Hendi M, Xu C, Wang L, Hou T, Si J, Chen S
Gut Microbes 2021 Jan-Dec;13(1):1-17. doi: 10.1080/19490976.2020.1826746. PMID: 33557671Free PMC Article
Ulcerative colitis: epidemiology, diagnosis, and management.
Feuerstein JD, Cheifetz AS
Mayo Clin Proc 2014 Nov;89(11):1553-63. Epub 2014 Sep 8 doi: 10.1016/j.mayocp.2014.07.002. PMID: 25199861
Chronic ulcerative colitis and colorectal cancer.
Rogler G
Cancer Lett 2014 Apr 10;345(2):235-41. Epub 2013 Aug 11 doi: 10.1016/j.canlet.2013.07.032. PMID: 23941831

Diagnosis

Microalgae-Based Hydrogel for Inflammatory Bowel Disease and Its Associated Anxiety and Depression.
Zhong D, Jin K, Wang R, Chen B, Zhang J, Ren C, Chen X, Lu J, Zhou M
Adv Mater 2024 Jun;36(24):e2312275. Epub 2024 Mar 18 doi: 10.1002/adma.202312275. PMID: 38277492
Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation.
Grubišić V, McClain JL, Fried DE, Grants I, Rajasekhar P, Csizmadia E, Ajijola OA, Watson RE, Poole DP, Robson SC, Christofi FL, Gulbransen BD
Cell Rep 2020 Sep 8;32(10):108100. doi: 10.1016/j.celrep.2020.108100. PMID: 32905782Free PMC Article
Approach to a Child with Colitis.
Palle SK, Prasad M, Kugathasan S
Indian J Pediatr 2016 Nov;83(12-13):1444-1451. Epub 2016 Apr 15 doi: 10.1007/s12098-016-2091-5. PMID: 27080713
Ulcerative colitis: epidemiology, diagnosis, and management.
Feuerstein JD, Cheifetz AS
Mayo Clin Proc 2014 Nov;89(11):1553-63. Epub 2014 Sep 8 doi: 10.1016/j.mayocp.2014.07.002. PMID: 25199861
Ischaemic colitis--review.
Dimitrijević I, Micev M, Saranović Dj, Marković V, Petrović J, Antić S, Sekulić A, Krivokapić Z
Acta Chir Iugosl 2008;55(3):89-95. doi: 10.2298/aci0803089d. PMID: 19069699

Therapy

Indol-3-Carbinol and Quercetin Ameliorate Chronic DSS-Induced Colitis in C57BL/6 Mice by AhR-Mediated Anti-Inflammatory Mechanisms.
Riemschneider S, Hoffmann M, Slanina U, Weber K, Hauschildt S, Lehmann J
Int J Environ Res Public Health 2021 Feb 25;18(5) doi: 10.3390/ijerph18052262. PMID: 33668818Free PMC Article
B. adolescentis ameliorates chronic colitis by regulating Treg/Th2 response and gut microbiota remodeling.
Fan L, Qi Y, Qu S, Chen X, Li A, Hendi M, Xu C, Wang L, Hou T, Si J, Chen S
Gut Microbes 2021 Jan-Dec;13(1):1-17. doi: 10.1080/19490976.2020.1826746. PMID: 33557671Free PMC Article
Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis.
Wu J, Wei Z, Cheng P, Qian C, Xu F, Yang Y, Wang A, Chen W, Sun Z, Lu Y
Theranostics 2020;10(23):10665-10679. Epub 2020 Aug 29 doi: 10.7150/thno.43528. PMID: 32929373Free PMC Article
Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer.
Zhang M, Viennois E, Prasad M, Zhang Y, Wang L, Zhang Z, Han MK, Xiao B, Xu C, Srinivasan S, Merlin D
Biomaterials 2016 Sep;101:321-40. Epub 2016 Jun 9 doi: 10.1016/j.biomaterials.2016.06.018. PMID: 27318094Free PMC Article
Ulcerative colitis: epidemiology, diagnosis, and management.
Feuerstein JD, Cheifetz AS
Mayo Clin Proc 2014 Nov;89(11):1553-63. Epub 2014 Sep 8 doi: 10.1016/j.mayocp.2014.07.002. PMID: 25199861

Prognosis

Claudin-2 protects against colitis-associated cancer by promoting colitis-associated mucosal healing.
Ahmad R, Kumar B, Thapa I, Tamang RL, Yadav SK, Washington MK, Talmon GA, Yu AS, Bastola DK, Dhawan P, Singh AB
J Clin Invest 2023 Dec 1;133(23) doi: 10.1172/JCI170771. PMID: 37815870Free PMC Article
Wumei Wan attenuates angiogenesis and inflammation by modulating RAGE signaling pathway in IBD: Network pharmacology analysis and experimental evidence.
Duan ZL, Wang YJ, Lu ZH, Tian L, Xia ZQ, Wang KL, Chen T, Wang R, Feng ZY, Shi GP, Xu XT, Bu F, Ding Y, Jiang F, Zhou JY, Wang Q, Chen YG
Phytomedicine 2023 Mar;111:154658. Epub 2023 Jan 12 doi: 10.1016/j.phymed.2023.154658. PMID: 36706698
Indol-3-Carbinol and Quercetin Ameliorate Chronic DSS-Induced Colitis in C57BL/6 Mice by AhR-Mediated Anti-Inflammatory Mechanisms.
Riemschneider S, Hoffmann M, Slanina U, Weber K, Hauschildt S, Lehmann J
Int J Environ Res Public Health 2021 Feb 25;18(5) doi: 10.3390/ijerph18052262. PMID: 33668818Free PMC Article
B. adolescentis ameliorates chronic colitis by regulating Treg/Th2 response and gut microbiota remodeling.
Fan L, Qi Y, Qu S, Chen X, Li A, Hendi M, Xu C, Wang L, Hou T, Si J, Chen S
Gut Microbes 2021 Jan-Dec;13(1):1-17. doi: 10.1080/19490976.2020.1826746. PMID: 33557671Free PMC Article
Approach to a Child with Colitis.
Palle SK, Prasad M, Kugathasan S
Indian J Pediatr 2016 Nov;83(12-13):1444-1451. Epub 2016 Apr 15 doi: 10.1007/s12098-016-2091-5. PMID: 27080713

Clinical prediction guides

Wumei Wan attenuates angiogenesis and inflammation by modulating RAGE signaling pathway in IBD: Network pharmacology analysis and experimental evidence.
Duan ZL, Wang YJ, Lu ZH, Tian L, Xia ZQ, Wang KL, Chen T, Wang R, Feng ZY, Shi GP, Xu XT, Bu F, Ding Y, Jiang F, Zhou JY, Wang Q, Chen YG
Phytomedicine 2023 Mar;111:154658. Epub 2023 Jan 12 doi: 10.1016/j.phymed.2023.154658. PMID: 36706698
BAFF Blockade Attenuates DSS-Induced Chronic Colitis via Inhibiting NLRP3 Inflammasome and NF-κB Activation.
Zhang Y, Tao M, Chen C, Zhao X, Feng Q, Chen G, Fu Y
Front Immunol 2022;13:783254. Epub 2022 Mar 7 doi: 10.3389/fimmu.2022.783254. PMID: 35320937Free PMC Article
Indol-3-Carbinol and Quercetin Ameliorate Chronic DSS-Induced Colitis in C57BL/6 Mice by AhR-Mediated Anti-Inflammatory Mechanisms.
Riemschneider S, Hoffmann M, Slanina U, Weber K, Hauschildt S, Lehmann J
Int J Environ Res Public Health 2021 Feb 25;18(5) doi: 10.3390/ijerph18052262. PMID: 33668818Free PMC Article
B. adolescentis ameliorates chronic colitis by regulating Treg/Th2 response and gut microbiota remodeling.
Fan L, Qi Y, Qu S, Chen X, Li A, Hendi M, Xu C, Wang L, Hou T, Si J, Chen S
Gut Microbes 2021 Jan-Dec;13(1):1-17. doi: 10.1080/19490976.2020.1826746. PMID: 33557671Free PMC Article
Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis.
Wu J, Wei Z, Cheng P, Qian C, Xu F, Yang Y, Wang A, Chen W, Sun Z, Lu Y
Theranostics 2020;10(23):10665-10679. Epub 2020 Aug 29 doi: 10.7150/thno.43528. PMID: 32929373Free PMC Article

Recent systematic reviews

SYSTEMATIC REVIEW AND META - ANALYSIS OF THE FREQUENCY AND RE-CLASSIFICATION TRENDS OF PEDIATRIC INFLAMMATORY BOWEL DISEASE - UNCLASSIFIED.
Bolia R, Goel AD
Arq Gastroenterol 2022 Oct-Dec;59(4):531-539. doi: 10.1590/S0004-2803.202204000-92. PMID: 36515348
Antioxidant therapy for treatment of inflammatory bowel disease: Does it work?
Moura FA, de Andrade KQ, Dos Santos JCF, Araújo ORP, Goulart MOF
Redox Biol 2015 Dec;6:617-639. Epub 2015 Oct 23 doi: 10.1016/j.redox.2015.10.006. PMID: 26520808Free PMC Article
Systematic review: colitis associated with anti-CTLA-4 therapy.
Gupta A, De Felice KM, Loftus EV Jr, Khanna S
Aliment Pharmacol Ther 2015 Aug;42(4):406-17. Epub 2015 Jun 15 doi: 10.1111/apt.13281. PMID: 26079306

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...
    -